Featuring Demian Dressler, DVM and Susan Ettinger, DVM, Dip. ACVIM (Oncology), authors of The Dog Cancer Survival Guide

Transitional Cell Carcinoma

Updated: November 14th, 2018

There is a whole team of dog lovers behind Dog Cancer Vet and DogCancerBlog.com, and we’re here to help, because we understand what it’s like to deal with dog cancer. We work for Maui Media, the book publisher which includes paperback and digital copies of the best-selling animal health book Dog Cancer Survival Guide: Full Spectrum Treatments to Optimize Your Dog’s Life Quality and Longevity. This must-read book is available everywhere books are sold in paperback, and digital formats (iPad, Kindle, Nook). It is authored by our veterinarian bloggers Dr. Demian Dressler, and Dr. Susan Ettinger, DVM, ACVIM (Oncology).

Transitional Cell Carcinoma (TCC) is a cancer of the dog’s urinary tract: bladder, ureters, urethra, or prostate gland. It’s aggressive and rarely curable, but there are many things you can do to help your dog’s longevity and life quality, just as with any other cancer type. There were many studies, articles and books Dr. Dressler and Dr. Ettinger used when writing The Dog Cancer Survival Guide. Here is a list of the most important references about Transitional Cell Carcinoma.

Please note that in vivo and clinical use citations were included whenever possible. We have also include links to the papers, where available. Most of the papers are found on the National Institute of Health’s online library, PubMed.

Bladder and Urethral Tumors. Henry CJ, in Henry CJ, Higginbotham ML (ed): Cancer Management in Small Animal Practice. Missouri. Saunders Elsevier 2010, p 290-296.

Tumors of the urinary system. Knapp DW. Withrow SJ, Vail DM (eds): Withrow & MacEwen’s Small Animal Clinical Oncology. St Louis Missouri, Saunders Elsevier, 2007, pp 649-658

Transitional Cell Carcinoma. Bryan JN, in Cote E (2nd ed), Clinical Veterinary Advisor: Dogs and Cats. Missouri, Mosby Elsevier, 2011, p 1112-1114.

Management of Transitional Cell Carcinoma. Henry CJ. Vet Clin Small Anim 33: 597-614, 2003.

Evaluation of a bladder tumor antigen test as a screening test for transitional cell carcinoma of the lower urinary tract in dogs. Henry CJ, Tyler JW, McEntee MC, et al.  Am J Vet Res 64:1017, 2003.

Epidemiologic study of insecticide exposures, obesity, and risk of bladder cancer in household dogs. Glickman LT, Schofer FS, McKee LF, et al. J Tox Environ Health 28(4):407, 1989.

Herbicide exposure and the risk of transitional cell carcinoma of the urinary bladder in Scottish terrier dogs. Glickman LT, Raghyavan M, Knapp DW et al. J Am Vet Med Assoc 224:1290-1297, 2004.

Evaluation of the effect of dietary vegetable consumption on reducing risk of transitional cell carcinoma of the urinary bladder in Scottish Terriers. Raghavan M, Knapp DW, Bonney PL, et al. J Am Vet Med Assoc. 227(1):94-100. 2005

Clinical evaluation of mitoxantrone and piroxicam in a canine model of human invasive urinary bladder carcinoma. Henry CJ, McCaw DL, Turnquist SE, et al. Clin Cancer Res 9:906, 2003.

Piroxicam therapy in 34 dogs with transitional cell carcinoma of the urinary bladder. Knapp DW, Richardson RC, Chan TC, et al. J Vet Int Med 8:273, 1994.

Canine bladder and urethral tumors: a retrospective study of 115 cases (1980-1985). Norris AM, Laing EJ, Valli VEO, et al. J Vet Intern Med 6(3):145, 1992.

Surgically induced tumor-seeding in eight dogs and two cats. Gilson SD, Stone EA. J Am Vet Med Assoc 196(11):1811, 1990.

Piroxicam, mitoxantrone, and course fraction radiotherapy for the treatment of transitional cell carcinoma of the bladder in 10 dogs: a pilot study. Poirier VJ, Forrest LJ, Adams WM, et al. J Am Anim Hosp Assoc 40:131, 2004.

Surgically induced tumor-seeding in eight dogs and two cats. Gilson SD, Stone EA. J Am Vet Med Assoc 196(11):1811, 1990.

Needle-tract implantation following US-guided fine-needle aspiration biopsy of transitional cell carcinoma of the bladder, urethra, and prostate. Nyland TG, Wallack ST, Wisner ER. Vet Radiol Ultrasound 43(1):50, 2002.

Evaluation of a bladder tumor antigen test as a screening test for transitional cell carcinoma of the lower urinary tract in dogs. Henry CJ, Tyler JW, McEntee MC, et al. Am J Vet Res 64:1017, 2003.

Radiographic appearance of pulmonary metastases from transitional cell carcinoma of the bladder and urethra of the dog. Walter PA, Haynes JS, Feeney DA, et al. J Am Vet Med Assoc 185(4):411, 1984.

Evaluation of carbon dioxide laser ablation combined with mitoxantrone and piroxicam treatment in dogs with transitional cell carcinoma. Upton ML, Tangner CH, Payton ME. J Am Vet Med Assoc 228:549, 2006.

Prognostic factors in dogs with urinary bladder carcinoma. Rocha TA, Mauldin GN, Patnaik AK, et al. J Vet Intern Med 14(5): 486-90

Canine transitional cell carcinoma. Mutsaers AJ, Widmer WR, Knapp DW. J Vet Intern Med 17:136, 2003

There is a whole team of dog lovers behind Dog Cancer Vet and DogCancerBlog.com, and we’re here to help, because we understand what it’s like to deal with dog cancer. We work for Maui Media, the book publisher which includes paperback and digital copies of the best-selling animal health book Dog Cancer Survival Guide: Full Spectrum Treatments to Optimize Your Dog’s Life Quality and Longevity. This must-read book is available everywhere books are sold in paperback, and digital formats (iPad, Kindle, Nook). It is authored by our veterinarian bloggers Dr. Demian Dressler, and Dr. Susan Ettinger, DVM, ACVIM (Oncology).

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