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Featuring Demian Dressler, DVM and Susan Ettinger, DVM, Dip. ACVIM (Oncology), authors of The Dog Cancer Survival Guide

Cancer Initiation, Promotion and Progression

Updated: October 1st, 2018

There were many studies, articles and books Dr. Dressler and Dr. Ettinger used when writing The Dog Cancer Survival Guide. Here is a list of the most important references about cancer initiation, promotion, and progression.

Please note that in vivo and clinical use citations were included whenever possible. We have also included links to the papers, where available. Most of the papers are found on the National Institute of Health’s online library, PubMed.

Mutation-selection networks of cancer initiation: tumor suppressor genes and chromosomal instability. Komarova NL, et al., J Theor Biol. 2003 Aug 21;223(4):433-50.

Genome maintenance mechanisms for preventing cancer. Hoeijmakers JH. Nature. 2001 May 17;411(6835):366-74. Review.

Cancer initiation and progression: an unsimplifiable complexity. Grizzi F, et al. Theor Biol Med Model. 2006 Oct 17;3:37.

Cancer as a complex adaptive system. Schwab ED and Pienta KJ. Med Hypotheses. 1996 Sep;47(3):235-41.

“Blazing a genetic trial.” Pines, M. Howard Hughes Medical Institute. http://www.hhmi.org/genetictrail/d100.html. Retrieved on 2010-6-25.

Cancer-related inflammation. Mantovani A, et al., Nature. 2008 Jul 24;454(7203):436-44. Review.

Molecular pathways and targets in cancer-related inflammation. Mantovani A, et al., Ann Med. 2010 Apr;42(3):161-70. Review.

The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance. Allavena P, et al. Immunol Rev. 2008 Apr;222:155-61. Review.

Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Colotta F, et al., Carcinogenesis. 2009 Jul;30(7):1073-81.

Emergentism as a default: cancer as a problem of tissue organization. Soto AM and Sonnenschein C. J Biosci. 2005 Feb;30(1):103-18. Review.

A Malignant Flame, Stix, G., Scientific American Special. 2008; 18(3): 48-55.

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