Keep Yourself and Your Dogs Safe with Palladia
Updated: October 10th, 2018
Palladia is the first FDA-approved drug for dog cancer. It is a chemotherapy medication, and as such it is a big gun.
When I say big gun, I mean that there are side effects and issues that you need to be aware of. And some of you may have not heard this yet. Since a goal of this blog and the Dog Cancer Survival Guide is to give you important information that you may have not yet heard, let’s look at Palladia.
When you give your dog Palladia, you should wash your hands with soap and water after handling. Better yet, wear gloves. This is because a small amount of Palladia could end up inside your body if you handle the medication with bear hands. Like many chemotherapy drugs, toxicities are possible, and there is no reason to be exposed to these materials if you are not undergoing treatment yourself.
The drug insert suggest that you keep the bottle away from children. Also remember to keep the bottle away from any other medication. Sometimes medications can be confused by us grown-ups too, and drugs like these need to be kept in their own secure location.
If you are pregnant, I would not even handle Palladia due to the possible effects on developing babies. The insert says that birth defects are possible if Palladia were taken during pregnancy.
Remember to never break or crush the tablets. This is because the drug will aerosolize (become an airborne powder) and may be inhaled.
According to the manufacturer, the “waste” products of a dog taking Palladia should be put in a sealed plastic bag for disposal. Gloves should be worn. This is fairly strait forward for feces, but I would assume urine is a waste as well. Thus, I would consider active urinary metabolites of the drug to be possible. Same with vomited material.
For vomit, bag it wearing gloves. Urine would be tougher to collect in a bag, and skin contamination is a risk. Thus I advise irrigating the urinated area well with water. This implies that dogs on Palladia living in homes with other dogs should be walked outside, separate from the others, for elimination of waste. It would be considerate for others in the neighborhood for you to carry a jug of water to irrigate the appropriate areas, in addition to your ziplocks.
Whenever you embark on a treatment for dog cancer, be your dog’s number one health care advocate. Get the full picture, weigh your options, and create an action plan.
All my best,
Dr D

Dr. Demian Dressler is internationally recognized as “the dog cancer vet” because of his innovations in the field of dog cancer management, and the popularity of his blog here at Dog Cancer Blog. The owner of South Shore Veterinary Care, a full-service veterinary hospital in Maui, Hawaii, Dr. Dressler studied Animal Physiology and received a Bachelor of Science degree from the University of California at Davis before earning his Doctorate in Veterinary Medicine from Cornell University. After practicing at Killewald Animal Hospital in Amherst, New York, he returned to his home state, Hawaii, to practice at the East Honolulu Pet Hospital before heading home to Maui to open his own hospital. Dr. Dressler consults both dog lovers and veterinary professionals, and is sought after as a speaker on topics ranging from the links between lifestyle choices and disease, nutrition and cancer, and animal ethics. His television appearances include “Ask the Vet” segments on local news programs. He is the author of The Dog Cancer Survival Guide: Full Spectrum Treatments to Optimize Your Dog’s Life Quality and Longevity. He is a member of the American Veterinary Medical Association, the Hawaii Veterinary Medical Association, the American Association of Avian Veterinarians, the National Animal Supplement Council and CORE (Comparative Orthopedic Research Evaluation). He is also an advisory board member for Pacific Primate Sanctuary.
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My 12 yr old English bulldog has a 4 inch chemodectoma. She had 2 liters of fluid drained from her abdomen yesterday. I have been reading about Palladium. Would that be appropriate treatment in her case.