There were many studies, articles and books Dr. Dressler and Dr. Ettinger used when writing The Dog Cancer Survival Guide. Here is a list of the most important references about the use of apoptosis, a completely normal, natural form of cell suicide that is biologically critical to health. In fact, the lack of apoptosis is a hallmark of all types of cancer, which is why exploring ways to turn it back on is a topic currently at the cutting edge pf cancer research.
Please note that in vivo and clinical use citations were included whenever possible. We have also include links to the papers, where available. Most of the papers are found on the National Institute of Health’s online library, PubMed.
The hallmarks of cancer. Hanahan D, Weinberg RA. Cell. 2000 Jan 7;100(1):57-70. Review.
Why target apoptosis in cancer treatment? Kasibhatla S, Tseng B. Mol Cancer Ther. 2003 Jun;2(6):573-80.
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Kerr JFR, Wyllie AH, Currie AR, British Journal of Cancer 1972, 26:239-257
Therapeutic targeting of death pathways in cancer: mechanisms for activating cell death in cancer cells. Tan TT and White E. Adv Exp Med Biol. 2008;615:81-104.
Targeting apoptosis pathways in cancer therapy. Fulda S and Debatin KM. Curr Cancer Drug Targets. 2004 Nov;4(7):569-76.
“Falling leaves”: a survey of the history of apoptosis. Formigli L, Conti A, Lippi D. Minerva Med. 2004 Apr;95(2):159-64.
Apoptosis, oncosis, and necrosis. An overview of cell death. Majno G and Joris I. Am J Pathol. 1995 Jan;146(1):3-15.
Apoptosis signaling in tumor therapy. Fulda S and Debatin KM. Ann N Y Acad Sci. 2004 Dec;1028:150-6.
Apoptosis in cancer. Lowe SW and Lin AW. Carcinogenesis. 2000 Mar;21(3):485-95. Review.
The molecular control of DNA damage-induced cell death. Coultas L and Strasser A. Apoptosis. 2000 Dec;5(6):491-507.
Role of alterations in the apoptotic machinery in sensitivity of cancer cells to treatment. Rodriguez-Nieto S, Zhivotovsky B. Curr Pharm Des. 2006;12(34):4411-25.