There were many studies, articles and books Dr. Dressler and Dr. Ettinger used when writing The Dog Cancer Survival Guide. Here is a list of the most important references about treating osteosarcoma.
Please note that in vivo and clinical use citations were included whenever possible. We have also include links to the papers, where available. Most of the papers are found on the National Institute of Health’s online library, PubMed.
Prognosis for dogs with appendicular osteosarcoma treated by amputation alone: 162 cases (1978-1988). Spodnick GJ, Berg J, Rand WM, et al. J Am Vet Med Assoc. 200(7):995-9. 1992
Alternating carboplatin and doxorubicin as adjunctive chemotherapy to amputation or limb-sparing surgery in the treatment of appendicular osteosarcoma in dogs. Kent MC, Strom A, London CA, et al. J Vet Intern Med. 2004 Jul-Aug;18(4):540-4.
Carboplatin and doxorubicin combination chemotherapy for the treatment of appendicular osteosarcoma in the dog. Bailey D, Erb H, Willaims L, et al. J Vet Intern Med. 17(2):199-205, 2003
Stereotactic radiosurgery for treatment of osteosarcomas involving the distal portions of the limbs in dogs. Farese JP, Milner R, Thompson MS, et al. J Am Vet Med Assoc. 225(10):1567-72, 1548. 2004
Four fraction palliative radiotherapy for osteosarcoma in 24 dogs. Green EM, Adams WM, Forrest LJ. J Am Anim Hosp Assoc 38(5):445, 2002.
Palliative radiotherapy for canine appendicular osteosarcoma. McEntee MC, Page RL, Novotney CA, et al. Vet Radiol Ultrasound 34:367, 1993.
Palliative radiotherapy of appendicular osteosarcoma in 95 dogs. Ramirez O 3rd, Dodge RK, Page RL, et al. Vet Radiol Ultrasound 40:517, 1999.
Interleukin-2 liposome inhalation therapy is safe and effective for dogs with spontaneous pulmonary metastases. Khanna C, Anderson PM, Hasz DE, et al. Cancer 79(7):1409-21. 1997