Featuring Demian Dressler, DVM and Susan Ettinger, DVM, Dip. ACVIM (Oncology), authors of The Dog Cancer Survival Guide.
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Neoplasene as a Dog Cancer Treatment

I received a question recently asking if I had heard of Neoplasene, so I thought I should post about it.

Neoplasene is derived from bloodroot, an old herb used by native Americans.  The stuff works but can be a bit much for an average dog lover to deal with.  Read on.

It is delivered to the dog cancer patient in a salve that is rubbed on the tumor, or pills, or can be injected in the vein or around the tumor.

It is different from so-called “black salve”, as Neoplasene is a specific extract of bloodroot, not the whole herb.  Only certain components of the plant are used.

There are a variety of successes documented, especially with tumors of the skin like fiborsarcomas, mast cell tumors, mammary tumors, and others.

Check out the photos on this link (you will have to scroll through the document towards the bottom).  A little warning: some of these photos are a little clinical (they might be a little yucky for some).

http://www.docstoc.com/docs/2978296/Discussion-of-and-Clinical-Guide-for-The-treatment-of-neoplasm

Neoplasene is for use under veterinary supervision only.  This is a good call by the makers of the product (Buck Mountain Botanicals). The reason for this is, when the ointment is applied to the tumor on the skin, the tumor cells start to die.

When the tumor cells die, the tissue tends to slough off.  A hole is left which needs medical attention.  This hole can be pretty big, especially if the tumor was on the larger side.  Sometimes the defect produced after large sloughs can go down to the bone.  Kind of heavy-duty for some dog lovers.

Other factors need to be considered before using Neoplasene.  One is that your dog must not lick the ointment.  An Elizabethan collar may be needed, sometimes for a long time.  Another issue is the wound may need twice daily care.  Finally, there can be pain or discomfort after application or use of Neoplasene, which may require the use of prescription strength pain control medication, in some cases.

Here is a link if you would like contact information for your veterinarian:

http://www.buckmountainbotanicals.net/treatments/neoplasene.html

Like many tools in medicine, we need to consider all the pros and cons of this treatment.  For some dogs with cancer and those who love them, it may be a great match, but not necessarily for all.

I hope this information is helpful.  For more outside the box ways to deal with canine cancer, check out the dog cancer e-book, The Dog Cancer Survival Guide, Beyond Chemotherapy, Radiation, and Surgery.

Best to all,

Dr D

About the Author: Demian Dressler, DVM


Dr. Demian Dressler, DVM is known as the "dog cancer vet" and is author of Dog Cancer Survival Guide: Full Spectrum Treatments to Optimize Your Dog's Life Quality and Longevity. Visit his blog and sign up free to get the latest information about canine cancer. Go to http://DogCancerBlog.com.

  • http://addieandhemangiosarcoma.blogspot.com/ Denice Key

    Our dog was diagnosed with hemangiosarcoma in July, 2008. She was given 8-10 week life expectancy. We did a lot of research and decide to use the neoplasene. For our dog, the cancer is in the blood, not external as you mention above. We give her oral dosage 2 times per day. It has been almost 9 months and she is still doing well. We could not find too much research on neoplasene with hemangiosarcoma, so we started a blog site on her progress: http://addieandhemangiosarcoma.blogspot.com/.

    Thanks for the website, it has been very helpful.

    Denice

  • Sandra

    My dog had two tumors removed (one from his leg and one from his neck) that were diagnosed as hemangiopericytomas. I was advised that we did not have clean margins on either tumor removal and to expect that the tumors will be back within three to nine months unless we opt for radiation treatments. I found a vet in Houston that was familiar with Neoplasene and he receives oral doses twice per day without any side effects. It has now been 14 months and still no sign of the cancer and he is more active than ever.

  • Charlien

    Sandra … I also live in Houston and have been searching for a Vet that is familiar with Neoplasene. Could you please post that Vet’s name here so I can contact them.

    I spoke with Dr. Fox this morning @ Buck Mountain Botanicals, the supplier of Neoplasene and he felt the injectable neoplasene in saline would work for my dog that has urethral cancer. My Vet is unfamiliar with this treatment so I’m looking for one here in Houston that is so I can discuss it with them.

    The different posts I’ve read of dogs using the Neosplasene seems to be with good results. Hope yours continues to be healthy.

    Thanks!

  • rxgirl1nm

    my 7 year old large breed mix was diagnosed last month with lymphoma and I am told he is stage IV because of all lymph node and spleen involvement. it is also possible he may have involvement in his lungs or some other unrelated lung thing going on because spots were seen on his lungs in the x-rays they did. my question is this: how can Neoplasene help him? I cant rub it on his spleen! (joke) how does it work when given orally? does it have a better success rate than the chinese medicine approach? I have him on omega 3 fish oils, l-glutamine, mushrooms, digestive enzymes, probiotics, garlic and homecooked food. How is the Neoplasene any better?

    thank you for your time

  • Charlien

    I spent days tracking down a Vet in Houston that would administer the Neoplasene treatment. I finally got the name of a Dr. Stiles @ Tanglewilde Clinic that has used it. She uses both traditional & alternative treatments in her practice. I am waiting to hear back from her … hopefully, today … to see how we can incorporate it into my Little One’s battle.

    Hi, rxgirl! If you are working with a Vet that is open to using Neoplasene, ask them to contact Dr. Fox and he will work with them to use the correct protocol. He suggested I print off the Clinical Studies and take it to my Vet. With it being lymphoma, it will probably be the oral doses. Check the Clinical Studies to see if there any other Vets have used in that manner. The other things you are using are pretty much inline with the other added treatments I’ve heard of to help slow the cancer growth. Good luck! I hope you find a way to keep your Doggie with you are a good while longer. Also >>> do read the blog that Denice (the first post here) has on her dog’s success with Neoplasene.

  • Lynne

    Rxgirl,
    How is your dog doing? Our Cairn was just diagnosed with lymphoma also and we are researching neoplasene and hope to start him on it soon. I am looking for others who have had success with this treatment for lymphoma. These are difficult days but we feel so fortunate to have had Parker for 9 years already and had his unconditional love. Lynne

  • Lori

    Hi Denice,
    I’m also using the oral neo for my 10 1/2 y/o girl diagnosed with transitional cell carcinoma. She had surgery in June to remove the mass but the biopsy was pretty bad. Started her on .3 cc’s on July 2 – she’s up .5 cc’s as recommended by my Vet in Pa. Can you tell me how much your dog weighs and how much you gave her throughout the course of treatment. Also, has your Vet given you any idea how long the therapy will continue? Mine said if it works the neo will probably be continued for the rest of her life. I hope your girl is still doing well – your post put a smile on my face and boosted my hopes. Thank you so much!

  • diane corbett

    is this treatment of Neoplasene a good treatment for nasal carcinoma?

  • diane corbett

    how do we get information for breed and weight on how to administer etc. for neoplasene

  • http://psdouglas141@juno.com phil Douglas

    Hello Dr. Dressler.
    I have a 7 year old golden retriever that was dianosed with fibrosing
    steatitus myositis inside of his abdomen area. The tumor has pockets
    of cancer inside, and the tumor itself is very firm and good sized.
    I was told by a doctor that the tumor very well may effect my dogs
    uninary track area soon as it continues to grow, and he said that
    the tumor will start to protude and press hard against his belly skin
    area. Surgery would be radical because of the size of the tumor and
    It’s location. It would call for lazering out the tumor and also
    some good tissue, leaving a big cavity inside of my dogs abdomen.
    I was told by the doctor that the cancer was a low grade cancer.
    A screen would need to be implanted to keep my dogs insides from
    falling out. I was told that their was a chance of life threatning
    infection after the surgery, and a chance that the removal could
    still cause problems with his uninary areas. The recovery would
    be very painful, lenghthy, and if not careful, the screen could
    come loose causing futher problems. I’m torn on what to do. I want
    to save his life, but the surgery may kill him. I’ve been trying
    proteolytic enzymes now for about a month to try to kill the
    cancer cells. I’m just not sure if I’m giving him the right dose,
    or if this will really help. I keep putting off the surgery. I even
    read about neoplasene, and other natural things. I also pray quite
    often. I know that you would need to see my dog to get a good idea
    of the size, location, and feel of thet tumor, but from your past
    experience, what would you suggest as far as the surgery option, as
    a posed to the neoplasene or other remedy to fight the cancer. Time
    is not on my side, and I do not want to lose my friend. Thank you.
    Phillip

    • Dr. Dressler

      Dear Phillip,
      the diagnosis tells me that the tumor cells were not submitted with the specimen to the path lab since they did not give you a cancer diagnosis. Fibrosing steatitis myositis means scar tissue around inflamed fat and muscle. You need re-biopsy. Once the kind of cancer is established, things may clarify a little bit.
      Whatever you do, make sure that you are dealing with a board certified surgeon for this. Remember also that 7 is about 3-6 years less than average life expectancy for a Golden.
      D

  • Nancy

    Hello,

    7 year old neutered male rescue beagle was just diagnosed (ultrasound guided biopsy) with carcinoma of the prostate. Researching different treatment options. In the mean time, he is on piroxicam, misoprostol, and primor (bloody urine / UTI is what led to us discovering the prostate tumor) and I also have him on saw palmetto, turmeric, maitake, and noni juice. Am very interested in Neoplasene. Any recommendation of a veterinarian in the seattle area that is familiar with it / has used it would be very welcome. Snoopy is a wonderful dog – he was my dad’s until my dad passed away in september so the diagnosis is especially hard. I had not planned on getting another dog after my Irish Setter lost her battle with osteosarcoma in 2000 and now I’d dealing with dog cancer yet again.

    Thank you,

    Nancy and Snoopy

    • Dr. Dressler

      Nancy
      One approach would be to contact Buck Mountain and ask for a reference for a vet, then have the vet call Buck Mountain after you bring your Snoopy in for an initial exam and consult.
      Best,
      Dr D

  • Karen

    Hello Dr. Dressler,
    We found out on two days ago our 11 year old golden retriever has oral cancer. We found it on the inside of her mouth inside her cheek. A little history about Chloe. 6 years ago she was undergoing a simple procedure and had an allergic reaction to the anesthesia. 5 years prior she had surgery and we didn’t have an issue. As a result of the complications in surgery they flushed fluids in to her. We didn’t find out for three days and many calls to the vet that the flushing had impacted her kidneys. In the three days she lost weight and everytime I called the vet they kept telling me it was because she still had some of the anesthesia in her. She had to be admitted to the hospital and on IV for four days. As a result she has been on special diet of Hills KD dog food.
    The vet told us if he removed it he would have to also remove part of her jaw. He said he didn’t think should would be able to handle all that surgery. He said the growth would continue to grow and she would die from lack of nutrition. He really did not leave us with any hope. We still have her on the KD dog food but have changed it to soft canned food. Do you think Neoplasene might be an option to slow the growth? We are willing to try anything.
    Thank you.

    • Dr. Dressler

      Dear Karen,
      well, this is a tough one. Neoplasene does indeed kill cancer cells, and I would bet that it would exterminate your dog’s cancer cells too. However, I have two concerns. One is that as the cells die, your dog might not want to eat, and this could take days. Secondly, with the tumor gone, a hole could be produced in your dog’s cheek that might need to be closed with a surgery. If the tumor is more invasive than just the cheek, the defect left could possibly be so large that it would not be repairable. This is a very tough call. I suppose if all other options were exhausted, and there were no choice, this would be an idea. You would need to be ready for these two issues though, and really need to ask yourself if they occurred, would you be prepared for them? If the answer is yes, and you are in a corner, it might be a gamble you are willing to take.
      I hope this helps,
      Dr D

  • Kurt

    Doctor D.
    I have a 6 year old JRT and she was diagnosed with bone cancer in her jaw. I called my vet after doing as much research as the internet would allow and told him about neoplasene. He called Buck Mountain and ordered the treatment for my dog. I am happy to say that she is doing well and the inside of her mouth is healing nicely. BTW she was not supposed to make it past Thanksgiving.

    Thanks for all you do

    Kurt

    • Dr. Dressler

      Thanks Kurt, glad things are going well
      Dr D

  • Heather Allen

    Dear Dr. Dressler,
    Is Neoplasene appropriate for internal usage? Eddie, my 11 1/2 year old Labrador has osteosarcoma and I’m pretty much willing to try anything. Traditional methods (surgery, amputation, chemo, radiation) are not really an option as his tumour is very large and located on his side, between his ribcage and hip. How would Neoplase work internally on something like this?

    Thank you for any advise you can give.

    Heather

  • http://www.foxtal.com Debra

    My 6 year old Belgian Malinois has a brachial nerve sheath tumor. Because of the location, injectable neoplasene is not a possibility so we have been giving her an oral dose twice a day. She is in good health and feeling spunky, and has outlived the predictions of the vets at the University Hospital who wanted to amputate the leg and essentially sent us home to manage the pain and die. I also give her Chinese herbs, as provided by my holistic vet and take her every two weeks for biocom treatments.

    What is your opinion of the biocom treatments? We did that prior to my vet learning about the neoplasene, and the treatments seem to have helped.

  • RC

    Dr. Dressler,
    Our 8 Yr old Black Lab was diagnosed with Nasal Adenocarcinoma last week. The Doctor said he removed over 90% of the tumor form his left nasal passage. They confirmed it had not spread behind his nose to the Cranial Plate and has not spread to his Chest. We visit our Oncologist tomorrow. Would Neoplasene be beneficial being that we may have caught it in an early stage and, if yes, how would it be administered?
    Thank you for your hard work and research!

    RC

    • Dr. Dressler

      Dear RC
      it can be administered topically (right on the site), and also orally and as an injected solution. Have your vet call Dr. Buck at Buck Mountain. I would consider its use in your case!
      Keep up your hard work too!
      Dr D

  • Kammee

    My dog has mast cell and was diagnoised last march and doing great. I used the neoplasene for some of the external tumors both injectable and salve, it worked great!. However there was alot of healing time involved as well as some surgery to repair what the neoplasese ate away from the cancer cells. Just relize sometimes this can make some horendous wounds but it also can be a great experiance simply because the tumors are now gone..My dog also took the oral neoplasese to. I raw feed Dannon my dog so I took the oral and put it in a sticky meat ball and threw it to him so he gulped it down. The taste of the neoplasene is horrible and can burn the mouth from my experiance so it is important to get them to swallow it in something. They trypically wont eat it in there food mixed with it, and squirting it into there mouth in my opinion isnt an option because of the nasty taste as well as the burning sensation. After using the product for 6 months I had great results but unfortunatly my dog became allergic to the oral.So we stopped the neoplasene and started on another product called Angiostop and Revivin. Both kill the cancer from many diffrent ways. Both are oral and holistic. You can find out more about these wonderfull products by visiting the web site
    http://www.DrChi-health.com The angiostop works on many various cancers with out the bloody wounds as side effects. I might add my dog Dannon is doing great after haveing a previous grim prognosis. The other thing that has really helped him is KAngen water. This is an alkaline and antioxigend water . Cancer cannot live in an alkaline enviorment or without sugar. Acidity increases disease as well as sugar. Dannon has great energy since adding the Kangen water he is back to his old self.

    • Dr. Dressler

      Dear Kammee,
      thanks for the info!
      Best,
      Dr D

  • Tammy

    Dr. D ~
    Our almost eight-year old spayed female Golden Retriever/Chow mix had surgery last Tuesday – Jan. 26th on a small soft tissue sarcoma tumor on her left front forearm. Biopsy results revealed the tumor as hemangiopericytoma with very narrow, but clean, borders of 0.1-0.4 on the edges and 0.1-0.2 deep. An integrative vet we are consulting with is recommending topical application of Neoplasene to kill off any remaining cancer cells. And, given the narrow clean margins, we expect there to be some.
    I’ve skimmed through the research document you referred to above, and am wondering if you think we should expect a large wound area on our dog(like the one shown for a nerve sheath tumor) given we successfully had the tumor surgically removed, and are now treating only the surrounding areas for possible remaining cancer cells?

    Given we’ve already completed the surgery, and are now treating only for random remaining cancer cells, do you think we need a treatment as strong as Neoplasene? Or, would you suggest we wait on the Neoplasene and instead implement a course of the Big Five for a period of time – as well as other supplements you recommend, along with a whole food diet, and assume that will kill any remaining cells quickly before a tumor re-grows?

    We’re open to risk – she’s healthy otherwise and only eight years old, but I’m wondering if we need to put her through some of the stronger treatment routes like radiation or Neoplasene if we can achieve remission through the supplements?

  • Renee Kendall

    I am in the process of trying figure what my 10 yr. Old Golden Retriever has on her left back hock. It started out as a hard lump which developed visually within about 6 months. When I realized it had become the size of about a walnut I took her in to my vet and they did a test on the fluid. The result came up as having some suspicious cells and further testing needed to be done. I needed to wait about a 1-1/2 weeks to have a wedge biopsy done, but in the mean time the lump went wild. It spread to about a 2″ by 3″ inflamed lump that continually drained from several spots. I had the wedge biopsy done and that showed the lump to consist of scar tissue and infection. She doesn’t limp at all, but her leg quivers when you go to touch the area, or she thinks your going to touch it. So started the antibiotics and anti-inflamatories. 3 months later and a second opinion vet, were still fighting this. We just did a bacteria test, that ruled out a bacterial problem. Now were doing a urine test for some other kind of possibility. The area just keeps on draining, so is my wallet. Personally I think its some type of Osteosarcama, especially after doing some research, thats when I came upon this site and Neoplasene.
    What do you think? Do you think that Neoplasene Salve could work for my Elsa. Please help.

    • Dr. Dressler

      Dear Renee,
      I think the vets are on the right track. Sadly, re-biopsy may be needed. You don’t want to start treating for a cancer unless you know definitively that you have a cancer….sounds frustrating. Hang in there and best of luck,
      Dr D

  • Jeannie Schmidt

    Dear Dr D,
    My 4 yr old Neopolitan/English Mastiff cross, Napoleon, started oozing bloody mucus from his right nostril a little over a month ago so I took him in and had him scoped. The vet said that there was too much blood and mucus even after several flushings to be able to see what was going on up there.(if it was a tumor or foreign body). He also did an xray of a broken tooth to see if it had abscessed but it wasn’t. He started him on antibiotics and had taken a sample for a slide but I wasn’t able to afford to send it to the lab at that time. About 2 weeks after he finished the antibiotics, Napoleon had a SEVERE nosebleed.He sneezed out a tumor about the size of a large blueberry or cranberry and a bunch of huge clots. Every vet I talked to told me to ice pack it because that is all they would be able to do to it. Nappy, of course, wouldn’t let me do that and as he weighs 177.6 lbs I couldn’t force him to let me. After 5 hrs of non-stop steady bleeding ( I was terrified he was going to bleed out) I finally found a vet close by that agreed to sedate him and give him some epinephrine to stop the bleeding. He gave me ace pills and more epinephrine to take home to control the bleeding. I had taken the tumor with me for him to look at but he refused to look at it because it had been in the freezer and he said that had ruined it. Well I had hoped that the tumor he sneezed out was what had caused it all and prayed that he would heal up now. Well 3 1/2 weeks later he had another bad nosebeed and sneezed out another larger tumor with crystal rock like clusters on it and lots and lots of clots again. This has me pretty much convinced it is cancer. I had this tumor sent to the lab and should have the results this friday. I had taken pictures of the first nosebleed into the vet and he said he had never seen any animal have a nosebleed as severe as Nappy’s was. The enclosed porch where I kept him when he had it looks like a body had been dismembered there. The walls and floors were completely covered in blood. I had to keep bringing him old comforters so he had a dry place to lay down and he completely saturated 5 of them.The vet said he didn’t think after seeing the pictures that there would be any treatment that could help him at this point. Nappy seems to be in perfect health most days, really playful,eating normally but most nights he has a very hard time breathing and has to inhale through his mouth. He will sometimes start a really loud, deep, wet, rattling snore and when he wakes up after that he gags and retches alot. I have been giving him shortening mixed with honey and a vitamin supplement to soothe his throat when this happens. I know this scares him because although he has always been my shadow he now doesn’t want me out of his sight. He has become a lap dog whenever possible. I am desperate to find a way to help him and feel so helpless as he and I sit up all night and I listen to him struggle for air. I am currently unemployed due to lay-offs and because the extra costs Nappy’s size incurs for all procedures I can’t afford more scopings, surgery, chemo and radiation even if it would be a possible course of treatment.I am praying that the Neoplasene could help him. I don’t want him to suffer or put him through painful treatments that will just prolong his misery. I haven’t been able to find a vet locally or in the surrounding areas that has had experience with the sudden onset of such severe nosebleeds and they are stunned by the size of tumors he has sneezed out. I would be extremely grateful if you would allow me to email you the pics of the nosebleed and of the tumors he sneezed out and get your opinion. If you think there is a chance that the Neoplasene or if there is any other therapy/remedy/treatment you think could save my best friend. I don’t know what to expect with this illness and at what point to say he’s had enough. It’s breaking my heart and I don’t know what to do. Please, I need some advice and will anxiously await your reply.
    Sincerely,
    Jeannie Schmidt

  • Sue Little

    For those interested in treatment with neoplasene, there is a good group on yahoo. Many of the pet owners there have prior experience using neoplasene and it is a good group for support and asking questions. It is Neoplasene_for-Cancer@yahoogroups.com.

    By far the most problematic is using the neoplasene orally. It is an emetic meaning it makes the dog nauseous and many times the animal will eventually refuse to eat. Many owners put the neo in cream cheese or butter. Things like that. A lot of people have had to stop with the neo and resort to other remedies such as Avemar and artemsinin.

    I would strongly suggest finding a vet with experience using neo. However, many owners convince their vets to order the neo for them sort of as a last resort, and often with a considerable amount of reluctance on the veterinarians part. Then when they encounter problems, the animal’s owner is sort of out there by themself.

    These are all lay people and NOT veterinarians but it is a good group and it does help to have people that have been through this before.

    Neoplasene, when it works, can seem truly miraculous. Just remember, there are also treatment failures. And Dr. Dressler is right. It is not for the faint of heart and can require a lot of committment, time, and stamina on the part of the owner.

    Hope this helps and I wish all of you and your babies the best.

  • Scott Harper

    Well, my dog started having minor nosebleeds once every day or two about 3 weeks ago, and my dad, who is a ENT actually took a sample of a small mass up in her nose just today. We sent the mass to our vet, who scheduled a surgery and will look at the biopsy results to see what treatments to use for her. Once I found out what was up with her, I went on the internet to look things up and found out about the drug Neoplasene. She is 11, but is in good shape, and other than the recent start of nosebleeds she hasnt changed at all. Im just hoping our vet or some vet near us can give us some info on this drug.

  • Donna Walker

    Dr.Dressler, Our 5 1/2 year old female (spayed)Golden Retriever Josie was diagnosed with grade 3 mast cell cancer. She has had two surgeries. One tumor was excised from right inguinal fold and metastatic inguinal lymph node. Abdominal ultrasound reveals multiple enlarged (approximately 3×4 cm and 2×3 cm) lymph nodes in the cell lumbar region along with a generalized hypoechoic appearance to the liver. The spleen is of normal size and echogenicity. Thoracic radiographs are unremarkable. This info was from a report from the Oncologist who examined Josie on June 26. The evening of July 2nd I noticed Josies lower belly area, right side swelled up and the skin is a dark red color. July 3rd, A.M. we think she has another growth(tumor). July 1st we met with a Holistic vet and she suggested that we research neoplasene. Josie is on the raw diet from your book and she is currently getting supplements along with Transfer Factor Plus.I just learned of another product from 4life called Canine Immune Tabs. Are you familiar with this? Also,Josie still has a great appetite and two of her three surgical sites have healed and she is full of energy(I worry about the one that has not healed) . Is Josie a good candidate for Neoplasene? I am willing and able to care for Josie 24/7. Please advise. I have clinical reports if you want to see them from June 26th. Thank You for your time Donna Walker

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  • cindy

    Our 8 year old lab/shepherd mix is on Neoplasene for osteosarcoma. She has been on for 11 days and her tumor size has more than doubled as well as a great deal of swelling below the tumor. I know Neoplasene causes inflammation which is why no NSAIDS but how long before we can expect to see the inflammation begin decreasing?

  • Celia Reich

    Our dog Hannah has had episodes of severe nosebleeds in the past two years. We have been trying to manage her condition with epinephrine. She forms a clot and sneezes and dislodges the clot and the bleeding resumes. After administering the epinephrine, we keep her calm in her crate for a couple of days and she usually has a month or so before another episode. Vet would like to do a rhinoscopy to collect a sample of nasal cavity tissue to determine if she has a tumor or if she has a fungal infection. This is quite a costly procedure. If she has a tumor, we are told it is quite difficult to do surgery in the nasal cavity and to treat with radiation. Is Neoplasene a good option for nasal cancer?

  • http://DogCancerBlog.com DemianDressler

    Dear Celia,
    it is critical to get a diagnosis first before contemplating any treatment for cancer. If your dog has something stuck in her nasal sinus, we could be missing the boat completely, or a fungal or bacterial infection.
    As to the question of “good option”, it depends what you mean by that. For a cure? No. You would be well served I believe, if this does turn out to be a cancer, to get some information about how to go about making treatment decisions, defining what your priorities are, learning what the survival statistics actually mean, and what all of the different options are with respect to treating cancer, which are many more than oral Neoplasene, although we still in medicine do not have a cure for non-removable dog cancers. For cancer, I would certainly consider the dog cancer diet, apocaps, ongoing doxycyline, immune stimulants (beta glucans), finding out whether local depos of matrix 3 cisplatin impregnated beads could be used to help control the growth of cancer (if it is found), and even contemplation of radiation therapy. But you first need to decide what your priorities are, what the statistics are, and how you are going to budget your dog’s care if cancer is on the table.
    I hope this helps…getting the data is step one…you could also find out if your vet is willing to do a sinus flush to try to get some cells out if cheaper than biopsy..
    Best
    D

  • bree

    hi i have a siberian husky n we found ut he has terrisible venereal tumor (TVT) and the chemo shots are very expensive so we r trying to find another option. would u recommend this for him? the pill?

    • http://DogCancerBlog.com DemianDressler

      Dear Bree,
      discuss with your oncologist using two doses of doxorubicin instead of the vincristine protocol as a less expensive alternative. Please read the Guide about how to lessen the side effects of this drug with supplements like Co Q-10, and be sure to use the dog cancer diet. In my patients I advocate Apocaps. Be sure each step you take is with your vet or oncologist supervising..Read this link too.
      Best,
      D

  • Tracy

    Hi. I am also looking into using neoplasene which was an option my vet gave me for helping treat his fibrosarcoma along his cheekbone. First he is going to have the tumor debulked. Then we are going to look at these options. Off hand what does it cost for treatments roughly for a 14 lb dog????

    • http://DogCancerBlog.com DemianDressler

      Dear Tracy,
      Please consult with your veterinarian on pricing as it depends on your dog’s specific care needs. I might also suggest your vet look into cisplatin impregnated beads available from Wedgewood pharmacy which can be implanted at the time of surgery. These act like local “deposits” of chemo drugs without the overall body side effects you see with IV injections or pills. I would suggest you also read The Dog Cancer Survival Guide as there are supplements (Apocaps and others), the Dog Cancer Diet, and other steps that could help your loved dog. Don’t forget to keep your vet involved in treatment steps for your canine companion!
      Good luck to you!

  • Laurie

    Our 10 yr old tibetan terrior has had a myxosarcoms since Jan 2010. The site is his rt foreleg at the distal joint. It was resected in Feb 2010 and reoccured by July and in beginning of Sept 2010 after visiting UC Davis they aspirated cells from his subclavicular lymph nodes which were positive. At this time we chose to try doxirubicin with a local vet. oncologist and after the first round there was not change in the tumor so he felt that it wasnt working and that the possible toxicity of it wasnt worth subjecting our dog – Petey . He recommended Paladia but we dont want to do this drug for several reasons, side effects, cost and the fact that he would have to be on it indefinately- thats even if he tolerated it & it worked????
    Can you suggest a treatment for myxosarcoms with metastasis? or a vet in our area that is open to alternative treatments, we live in the San Francisco bay area CA. Im an RN and dont want to cause more problems for our Peteyboy but want him to have a chance of enjoying more life with us and if thats not possible than a plan or understanding of a good death- is there hospice for dogs?
    Thanks,
    Laurie

  • Jennifer

    My dog is a 4 year old Newfoundland that had a turmor removed from left rear leg. Her vet removed it all with clean margins. Now we had another tumor removed in the same leg a bit higher then the last. This time it was too deep into the muscle tissue to get clean margins. Do you think this neoplasene will benefit her?

  • Brigitte, Moon’s Mom

    Hi Dr Dressler

    My 11ish year old dog Moon was diagnosed early December as having Nasal Carcinoma. (I don’t know exactly how old he is because I found him on the street in 2000). The carcinoma was said to be midway up his snout and towards the back… He currently has little to no air flowing through that nostril :(

    I decided against radiation and wonder how and if Neoplasene could help a dog with his type of cancer. What could I expect and how can I make it as comfortable as possible while he is being treated with Neoplasene. I really want to help him and don’t want to regret not trying something that could have worked… Also, im curious about where the “debris” from the cancer within the nasal canal would go once it is broken down? Its seems like a challenging area.

    Lastly, I purchased several supplements including Artemisinin & Vascustatin. I give him the Arte & vascustatin by mouth. The challenge I am having now is that he refuses to eat his food with the other immune supporting supplements. For most of his life he ate a raw diet and did really well on it, but since I started adding supplements to his food, he now refuses to eat it. I know its hard to help a dog from a distance but I wonder if you have any suggestions on what might be the most important supplements to get into him for his particular cancer?

    Thank you for your time,
    Brigitte, Moon & Scooter

  • Debi

    I have a soon to be 5 year old Irishwolfhound who was diagnosed with osteosarcoma and had a limb spare surgery to her right radius. The tumor had wrapped around her ulna and while trying to remove it the bone broke and a portion of the ulna was also removed. She has plates to both bones now.
    She was started on carboplatin and had 3 IV treatments. She then developed a metastatic skin tumor next to the first incision. She had surgery to remove the tumor even though there was very little skin for closure. This went well, but because of the aggressiveness of the cancer our oncologist decided to try injecting 5 FU intralesionally. This only lasted for 2 injections because the area became red and inflamed. About 2 weeks later an area of the skin on the side opposite from the metastic lesion opened up. I have been doing daily drsg changes and she had been on 4 different antibiotics, but for 4 days she is down to just Baytril. The open area initially would drain a large amt of red/tan liquid-not pus. The infection followed along the plates and I was able to express quite alo t of drg until after the Baytril was ID’d as the appropriate drug. A few days ago a spot on the skin below the healing open area turned black and with the next drsg change it sloughed off. I asked about starting another antibiotic and today Dr Tripp, our oncologist told me about Neoplasene and asked me to think about. My biggest worry is the open area getting bigger over the plates that extend from her foot to her elbow. Can this be controlled with good wound care? I dont want to cause her to suffer anymore then she already has. She’s doing well, and walks on the leg well most of the time. Can you give me any thoughts about using Neoplasene. She’s had 4 doses of Paladia so far. Thank for any info you can give me

    • http://DogCancerBlog.com DemianDressler

      Dear Debi,
      If time does not fix this (and allowing the Baytril to work), Neoplasine is a consideration, although it can be a bit rough. Have you read the Guide (click here)? Is your dog on immune enhancing beta glucans? How about Apocaps (click here)? Pain control?? Omega 3′s? Diet? Artemisinin? If this were my dog, I’d be using all of the above. As a last resort, amputation (see this post). You can do searches in the blog too using the search bar on the right side.
      All steps should be done under veterinary supervision.
      Best,
      Dr D

  • Debi

    My dog Jinx, a golden retreiver, was diagnosed with lymphoma just over a year ago and started people chemo immediately. Her white blood cell count went so low that the vet took her off of the medicine, and sent her home to die. I discovered neoplasene through a holistic vet and it has been a godsend. Jinx is still alive, happy and spunky. We do the oral application and have done 3 injections of lymph nodes as well. The injections are rough- seriously bad. The holes that opened up on her shoulders were large enough to put an orange into. The mess was gross, and it flipped my stomach having to reach my finger inside her body to apply the salve inside the holes. But it’s all worth it once the hole heals and the swelling goes down because she goes right back to being her old funny self. The cost is steep, but for us she’s like a child. I wouldn’t do it any other way.

  • dianelys

    Hello Dr. Dressler,

    I wanted to find out if the Neoplasine was proper for my 7 year old Rott Rex. He had an x-ray done on 01-11-2011 and the vet told me that it was bone cancer (osteosarcoma). It all started in Dec when he started limping and I could see that it was his right front leg. I took him to the vet on Dec 31 and they gave me some meds for the inflamation and pain but then about 2 weeks later he started throwing up and had bloody diarrhea so I took him to the vet on 01-11-11 and they took the x-ray where it showed the cancer mass. It is on the right leg (radius) area and the bone as already taken a different shape. Anyway I saw that a lady name Cindy on this web site had a similar story and had her dog on Neoplasine and she was asking that her dog had alot of swelling and she was wondering how long until it stopped and got better. could not find a response for her questions. I have not seen a lot of cases of dogs doing that med for that type of cancer and was wondering if I should give it a try. I can see that it is becoming harder for him to walk, but he still eats and walks and trys to be himself. I need all the help that I can get on this because amputions is not an option for us because of money issues. Thank you for all your help, Dianelys Miami, FL.

    • http://DogCancerBlog.com DemianDressler

      Dear Dianelys,
      the most important thing is that your vet is involved. If you do not have other options, Neoplasine may have some benefit. We cannot promise a cure, but it is worth a try. Don’t forget diet, Apocaps, and the other supplements in the Guide too!
      Best,
      Dr D

  • Jeannine M. Sovet

    Dear Dr. Dressler,
    My 12 yo Bichon Stella was diagnosed with Mast cell on her (L) hind leg in Aug. 20, 2010. She had a wide margin excision on 09/2/10 which came back as grade 3 with dirty margins and lymph node involvement. I found your website and ordered your survival guide. I started her on your cancer diet right away. I also started her on K9 immunity plus, milk thistle, a multivitamin, benedryl(25mg) tid, Cimetidine(200gm) bid , and 1000mg fish oil tid. I got her into an oncologist and he started her on masitinib on 9/23/10. Her tumor was already starting to grow back at this time. Two weeks after starting her on Masitinib her enzyme livels in her liver started to elevate so we discontinued treatment and the following week when I took her in to see the oncologist we started her on the triamcinolone injections which she has been getting every two weeks since then. Now it Jan.22, 2011 and it looks like the injections may not be working anymore.. Twelve days from her last injection her tumor grew so large and looked so mean and she was in pain so I rushed her to the vets… The oncologist said we would probably have to start thinking about what are next options are for my little girl… The injection brought it down to about 50% it usually brings it down 75% and it still looks very angry. She is still a very happy, energetic dog, still full of life and still getting into trouble(Stella’s usual). I’m scrapping the bottom of the barrel to pay for her vet bills. Is their anything else you can recommend we try? Do you think Neoplasene would work for her and if so is there a concern with the size of the tumor and the histamine reaction ? If the injections are not going to work to keep her tumor at bay and it gets any bigger then it did the last time I fear I will have to put her down due to the pain it is causing her. The thought that I will have to put her down while she still has so much life in her just kills me. I would do anything for my little girl but i will not let her suffer in pain… Please Help..

    Sincerly,
    Jeannine and Stella

  • Mary

    Dr. Dressler,

    My 10 yo Golden has masses in his nasal cavities. He had a rhinoscopy done and levage collected, biopsies taken and sent to a histopathologist, etc, but *no* cancer cells were evident from the samples. It has been several months and there is no alternative left but cancer, but obviously we do not know what type it is. My vet gave me the information on Neoplasene a few days ago, and I want to call her tomorrow to ask her to help us get started soon. The bridge of his muzzle behind his nose is starting to well up with painful tumor growth, and he is having a more difficult time breathing. His rhinoscopy was done by a different vet (who I was not very pleased with). I have seen in the comments here that you want to be 100% sure of the cancer diagnosis before proceeding with a cancer treatment. What if we are close to 100%? I do not think we can afford another rhinoscopy, disregarding the fact that my vet will be extremely reluctant to do another one to him, as his age/situation puts him at risk for a not-really-needed procedure. Besides that, if we do start the Neoplasene, I am scared about what might happen to him in the necrosis process. I am hoping that the salve can be applied on the top, and maybe a rhinoscopy-type procedure to do some local injections inside the nasal passage, but if all of the tumor doesn’t slough off the top… I really hope he doesn’t have a serious nosebleed. He has had one transfusion already from the nose issues.

    Hope to hear from you soon,
    Mary and Buddy

    • http://DogCancerBlog.com DemianDressler

      Dear Mary,
      this sounds like a tough situation. Have they done cultures? Blood work or titers to make sure this is not fungal?
      These would be some initial thoughts…
      I hope this helps
      Dr D

  • Hunter

    Hello Dr Dressler,

    I’ve not yet gotten the diagnosis of cancer, but I’m preparing myself for the worst. I have a 3y 10m GSD male, intact, that has had hematuria since Dec 2009, possibly earlier. Was first treated as prostatitis with antibiotics, when a year of of and on treatment had no effect, we went to deremaxx when the bleeding peaked during my female’s first heat cycle. 5 months went by with no symptoms, and then they came back in force when she got close to her next heat cycle. Did an ultrasound, and this showed a large prostatic cyst. Took him to a theriogenology school where a second ultrasound and fine needle aspiration showed 47ml of fluid extracted from a 7cm cyst. The cytology of the cystic fluid showed 50% lymphocytes, 29% large mononuclear cells, and 21% abnormal cells. Atypical cells were multinuclear, large to giant, marked anisocytosis and anisokaryosis, stippled chromatin and single pale purple nucleoli. Patholigist’s report suggested transitional cell carcinoma or adenocarcinoma of the prostate, or metastatic neoplasia. Pathologist said cells distinctly looked like what he would see in a seminoma, but palpation and measure of testes is normal. Ultrasound of everything, and tissue samples are to be done on March 22nd. Ultrasound showed no abnormalities of the rest of the prostate, or surrounding organs. We have since started finasteride daily, 5mg. Is oral neoplasene something we should/can consider in parallel to other treatments? Dog has no abnormal behaviour other than the hematuria, occasional weak urine stream and difficulty defecating, which have all stopped since the large cyst was drained.

    • http://DogCancerBlog.com DemianDressler

      Dear Hunter,
      these are tough ones. Intraoperative radiation may be an option. I would also focus on diet (you can download it free from the top of this web page). Apocaps may provide benefit. Also mitoxantrone and piroxicam are other options to consider. Drop the dose of Apocaps to 1/4 the labeled dose and give with food if using with piroxicam. I would also get the Guide for some other steps to help support your dog’s health.
      I hope this helps,
      Dr D

  • Tiffany H

    Dear Dr Dressler,

    My Dog Chopper started limping about a month ago, when I examined his foot it appeared his toe nail was split. I thought nothing of it and figured he had dug on something rough and it would heal with time. Well two weeks later I noticed he was still limping and examined his foot again only to notice his toe nail completely gone and split open. I took him to the vet immediately and she assumed it was an infection and put him on a very strong antibiotic and advised me to soak it in Epson salt water 2x a day for 15 mins at a time.

    I did all of this and a week later it is not looking any better she is now thinking it is a tumor or Osteosarcoma. She advised me of this buckmountain botanicals and said “she had not tried it, but was very impressed with the results” She spoke with Dr. Fox regarding the dog and he wanted pictures. She called me and notified me of what he needed and advised me to call him, and possibly he could reassure me of the results and advise me on treatment success.

    Needless to say it was the worst conversation I have ever had. Dr Fox was extremely rude and unprofessional, I understand I am not a vet, but he treated me as if I was unworthy of his time and why would I every think I was good enough to talk to him. So I would just like to let you and everyone else know before you promote this company you may also want to give a Warning….. to go with it. Never call and ask question because you will be treated very disrespectfully and will not receive any useful information regarding the product. Obviously only the vet should call.

    So if you have any other information on a treatment program that does not involve Dr.Fox I would greatly appreciate it. Also, any information you can give me on what I could possibly due to help my dog would be greatly appreciated as well. The wound is just not healing at all.

    • http://DogCancerBlog.com DemianDressler

      Dear Tiffany
      Well, Dr. Fox can sometimes not be the most delicate, but he has a good heart. Not sure if you noticed, but in the blog post about Neoplasene my suggestion was to have the vet do the talking, as you pointed out in your comment! At any rate, there may be a few missing steps here that are worth considering. First, a swollen digit with a wound or ulceration may or may not be cancer. There are subungual cysts which look all the world like cancer, but you remove the problem and they are gone, permanently. Sometimes you may have a resistant bacterial, or fungal infection. Were X-rays taken? This is a pretty important step that should not be overlooked first, as the appearance on the film can be useful. If this were my dog, I would have X-rays, a cytology of any discharge done, as well as cultures. If the digit looks cancerous after this, removal is the way to go, with biopsy. Only with a cancer diagnosis will we be justified in using cancer treatments, including Neoplasene if appropriate given the info you will have, and the many others out there which could be more appropriate.
      I hope this helps,
      Dr D

  • Mary

    Dr. D,
    Thanks for your response. Yes, we have had cultures and bloodwork done for possible bacterial or fungal infections. Nothing was found. This was done for sure at the rhinoscopy and I think they had cultured from his nose and looked at blood before that as well. We are actually on day 11 of Neoplasene now. In addition to the nasal cancer, Buddy had a large ear hematoma that was extremely persistent and treatment was having no effect on it. A little after 12 hours into his Neoplasene treatment, the aural hematoma was reduced by about 40%! Take into account that the hematoma was extremely persistent over a course of weeks, never going down even slightly, only getting bigger. After draining, he would have only a few days of reprieve. (His other ear had already experienced this and had the quilting surgery done.) Now, on day 11, it is maybe 10-15% of its pre-Neoplasene size. We are treating with oral Neoplasene and nose drops of the 3:1 Neo/saline mix. Buddy’s breathing has improved as well. Sneezing is reduced, he can sleep deeply breathing with his nose, hardly pants, and the noise his nose makes is a normal breathing sound now, just louder than true normal. He is tolerating the treatment extremely well and is feeling significantly better. If you would like more info on his situation/treatment/updates, I would be happy to elaborate.

    • http://DogCancerBlog.com DemianDressler

      Dear Mary,
      that is great news!
      Keep it up.
      Best,
      D

  • Kathy

    Dear Dr. Dressler,

    My dog was diagnosed with a TCC bladder tumor. My vet has been treating him with 5mg piroxicam and bladder infusion therapy of neoplasene. I read that piroxicam should not be given with neoplasene. Is this true? My vet said that it is true only if oral neoplasene is used. Also I wanted to know can I give my dog graviola extract with the neoplasene?

    Thank you,

    Kathy

  • Jamie Cole

    My son’s 12 yr old german shepard mix has a soft lump on his rib. What is the least expensive, least invasive start for diagnosis? How can we find a vet in Asheville, NC who is holistic, or may know of this treatment?
    Jamie

  • Jennifer

    Hello,

    Are there any known veterinarians in Europe working with neoplasene ? I live in France and my dog has an inoperable tumor on his C1 vertebrae, which has not been diagnosed conclusively as any 1 cancer – they gave a possibility of 3 different ones based on the biopsy (4 samples were taken), and decided probably histiosarcoma as he is part Bernese Mountain Dog but possibly also osteosarcoma. There is bone damage now as the tumor has become invasive.

    We put him on a phosphate treatment to prevent further bone loss and help the pain, but they say there is no hope and he is on metacam for pain and to keep down inflammation. I am not sure if neoplasene could even be recommended due to that fact, but thought I should explore the option at least.

    We have also given him what we can find in France of the treatments you recommend and he has eaten a mix of raw/natural diet since birth, though now we have removed the rice from his meat/vegetable stew mix. We know from his symptoms that he has had the tumor for more than 1 year, closer to 2 now before it was diagnosed (we thought he had hurt his neck wrestling for a stick with another dog and a osteopathic vet treatment would normally make him feel better for many months, then weeks, then the pain became more constant and we had a scan done). As far as they can tell it has not spread anywhere else and his blood work and kidney function is still normal. It has been 4 months since diagnosis and now he is starting to have paralysis effects such as dragging feet. I know it is probably hopeless but thought I would see if you know if there is anyone here in Europe working with some of these treatments. His energy and appetite is really good, and he is on shi-take and curcumin but apparently the tumor keeps growing, or he would not be having paralysis symptoms.

    • http://DogCancerBlog.com DemianDressler

      Dear Jennifer,
      have you read the Guide? Considered Apocaps? I believe they can be secured in Europe. I am not aware of vets in France using Neoplasene, however, this does not mean anything. I would have your vet contact Dr. Fox at Buck Mountain. The procedure is not hard. Might consider doxycyline as well, and red clover on top of the other items, under veterinary supervision.
      Best,
      Dr D

  • leslie

    My dog had a massive tumor on the side of his neck. The vet removed what he could and we are doing Neo treatment. Chaser’s neck is really swelling up due to this, but I have heard that is what happens when on this medicine. How long will there be swelling and will it start to go down? It has been about 3 weeks now and the swelling is bigger than the tumor was.

    Thanks

    • http://DogCancerBlog.com DemianDressler

      Dear Leslie
      I am sorry but I am not sure exactly how to give you the details you wish. I would most certainly have a recheck scheduled with the veterinarian who can best ascertain the reason for the swelling and thus give you the information you need. There are several possibilities but I am not sure which is active in your dog.
      Best
      D

  • Aaron French

    Dear Dr. D.
    Our Golden Retriever was just diagnosed with cancer, I don’t yet know the details of the type, but they found it on x-ray in his shoulder. He was going to this Vet. for acupuncture and I insisted for an x-ray, and this is what we found. My dogs current Dr. is a homeopathic vet., and we will bring our dog back to him. But they recommended a number of agents Neoplasene being one of them. Also Wei Qi Booster & Bone Stasis. Could you share your thoughts with me on how we should progress? I do not know if there is any metastisis as they only x-ray his shoulder. We are very upset and want to know what path to go down. Your thoughts are appreciated. Aaron

    • http://DogCancerBlog.com DemianDressler

      Dear Aaron,
      I will post about this. There are a couple of underlying items that deserve attention here…
      Dr D

  • Seren’s Mom

    My best friend is a 13 year old border collie x. She had surgery Sept. 17, 2009 to remove a mass that ended up being liposarcoma. My vet got all of the tumor that she possibly could during a lengthy surgery. This tumor was extensive and difficult to remove and the doctor was sure that she did not get clean margins. She also thinks the same cancer was in her abdominal cavity. Serendipity almost died during this surgery but had a remarkable recovery. In late March of this year (2011), Seren started coughing and we went to the vet and got temaril-P and doxycycline. She got better quickly, but about a week after she finished the meds, the cough came back, she was very restless at night, and her breathing became rapid and noisy. We went in on Tuesday, April 19 and got chest xrays which showed a large tumor(s) in one of her lungs and lots of fluid in her chest. The doctor removed 12cc of fluid and started Seren on furosemide and amoxicillin. Seren felt better after the fuild removal and we went back for more xrays on Mon., April 25. The lab did not detect cancer from the fluid submitted but we think it is liposarcoma again. The vet did not attempt to get a tissue sample because of all the blood tinged fluid. Surgery is not an option so I have started Seren on algae derived DHA, K9 Immunity and Transfer Factor yesterday, and will start fish oil and Apocaps today. I have ordered artemisinin but don’t have it yet. Serendipity takes Metacam every day for arthritis and has for years. She is taking furosemide and amoxicillin also. She has started eating Science diet n/d. She weighs 52 lbs. My plan is to keep up this regimen cutting back the Metacam to 40 lbs. and giving only 1 apocap 2x/day instead of 5/day. I will give Apocaps for 5 days and then drop it and start artemisinin for 5 days. I will alternate these on that schelule. What do you think of using pill pockets with some of these capsules? We used topical neoplasene on my beagle x to remove a non-malignant tumor and it worked great the first time. About a year later, that tumor came back and the neoplasene did not work. His toe had to be amputated. My vet has used neoplase orally for a dog with osteosarcoma but it didn’t seem to have much of an effect. I am interested in your thoughts about what I am going to do for Seren and your opinion of neoplasene for her.

  • Lynda

    Our pit mix has a Mast Cell Stage 3 (I found it last year and reported it as it grew, but they weren’t concerned). He had surgery, my super wonderful vet thought she’d gotten it all, but pathology says no. His ultrasound suggests it hasn’t spread, everything looks great. My holistic vet wants us to use Neoplasene and stop all vaccines. We have him on double K9 Immunity Plus and will add Apocaps if that’s ok, and have moved him to a grain-free diet hoping to get him on the cancer diet (I’ve ordered your book, haven’t read it all yet). What is your take on oral Neoplasene currently? I’ve also gotten Artemisinin and Curcumin but am not sure if I should start dosing. My traditional vet and oncologists are wary of it and will be about ceasing vaccines, I’m sure. Is that really necessary? He is his hungry, lazy, 60 pound self—I am pretty bummed and hating the East vs. West dichotomy. This is my third cancer dog and we live pretty close to power lines, so I wonder if that’s why. The incision site shows no regrowth—Triamcinolone? So many paths!

    • http://DogCancerBlog.com DemianDressler

      Dear Lynda
      Sorry to hear about your pit bull. Stage 3 would seem pretty concerning, but hindsight is 20-20, right? It can be very, very difficult to remove a grade 3 MCT during surgery, so don’t be too hard on your vet.
      If you have a grade 3 with dirty margins you know that there are cancer cells in your dogs body. This is a given.
      You should get a scar revision (removal of the tissue around the old incision) as you know there are cancer cells there.
      I agree on stopping vaccinations.
      I agree on Apocaps and K-9 immunity but use the unflavored one without the sugar (old formulation).
      I would consult with an oncologist and consider chemo before Neoplasene.
      If you opt against chemo, then consider Neoplasene.
      Don’t bother with curcumin as Apocaps has plenty.
      I would hold off on the artemisinin.
      Of course you have changed his diet, and are paying attention to the other things in the Guide…right…?
      Best,
      Dr D

  • Maciej

    Hi,
    My 12 y/o daschund was diagnosed with an anal gland adenocarcinoma. No obvious metastasis. He had a surgery on 4/20 (tumor only 1.4 cm, but margins were not clean), now scheduled for CT and 20 treatments of radiation therapy (I shiver when I think of it, but as I was told dogs are tolerating it quite well); possible chemo after radiation therapy. My board certified oncologist/radiation oncologist thinks that he has an excellent prognosis.
    I ordered K9 Immune Plus, Dr. Goodpet enzymes, Apocaps, Neptune Krill oil. I started him on the diet recommended in your book. Should I add Lutimax/Artemisinin? Doxycycline? Anything else? Will discuss Neoplasene with the oncologist on Monday.
    Please advice. Thank you.

    • http://DogCancerBlog.com DemianDressler

      Dear Maciej,
      so sorry to hear about your little one.
      Dont’ forget…diet!
      There is no need for Lutimax with Apocaps. Also I prefer the K-9 immunity without the added sugar (the old product with only the mushroom extract). I think the immune stimulation plus Apocaps plus diet, fatty acids and enzymes along with the conventional options sound like a good plan to me. Of course, discuss all with the clinician whose hands are on your dog.
      Best,
      Dr D

  • Nathalie Raadschilders

    Dear Dr. Dressler,

    We are from the Netherlands and our English writing is not so good so we hope you will understand what we mean.

    Today July the 26 our dog (West Highland terrier) hase been operated at a tumor inside his colon (rectum). this Friday or Monday we’ll know more about this tumor.
    Looking for answers we arrive at your site. Our question now is what can we do if it is a malicious kind of cancer?
    What alternative is there for chemo?
    We have read about neoplasene on your site but I (yet) dont know anyone who applies this in the Netherlands. Do you know someone who has experience in the Netherlands with Neoplasene or do you have another alternative?
    We really hope you can help us!

    Greetings from the Netherlands

    • http://DogCancerBlog.com DemianDressler

      Dear Nathalie,
      The answer to your question is a very long one (so long it filled a book!). We do not usually try to replace chemo- we use all the tools available since we do not have a cure for systemic or aggressive cancers if they cannot be totally removed with surgery. What type of cancer? Were the margins clean and wide? Is a second surgery needed? These are the first steps.
      I have little knowledge about vets in the Netherlands I am sorry to say. However, the use of Neoplasene is not difficult for a veterinarian. Have your vet contact Dr. Terrance Fox at Buck Mountain for more details. Don’t forget diet, apoptogens, immune support, and deliberate steps to increase life quality as discussed in the Guide. You can also search for general information about these in the blog.
      Best,
      Dr D

  • Betsy

    We got the bad news that our siberian husky 12 years old has nasal cancer. We were given 3 options: 5 doses of radiation, 21 doses, or put her down. We have spent $ 11,000 on this dog and our dog’s ailments( they 13 year old had a benign tumor on her liver) including the MRI for this one’s diagnosis. We were told that it would cost about 6-8 thousand more for radiation treatment that may or may not work. Does Neoplasene work for nasal carcinoma? And will it be very expensive? I really do not like the idea of radiation and its side effects-I was hoping that there would be the silver bullet of some kind of natural remedy, but to date nothing has been discovered that we can use to heal our pup.The sad thing is we used a better brand dog food to avoid cancer. I have lost faith in most things, as most “cures” are tied to multi-level selling products. Just trying to get money out of people who are desperate for hope.

    • http://DogCancerBlog.com DemianDressler

      Dear Betsy,
      I am sorry you are dealing with this. You are not alone.
      We don’t have a reliable cure for systemic cancer. However, there are things that can help extend life and keep it at good quality. We must be careful to define “work” as extending life with good quality. Neoplasene can help, especially if combined with the cancer diet, immune support, apoptogens, deliberate efforts to increase life quality daily, and the other approaches in the Guide. There is some evidence that combining IV vitamin C with IV Vitamin K3 can help as well. Keep in mind that nasal bleeding can be a side effect with this combo. Use all treatments under veterinary supervision.
      Best
      D

  • http://indyandcaninecancer.blogspot.com Indy

    Dear Dr. Dressler,

    I have a nasty one. A 9 year old male Golden Retriever with Histiocytic Sarcoma. He had a splenectomy last month to remove two tumors and his spleen. The largest was 12x12cm. We were fortunate and found Addie’s blog and came across Neoplasene the same day that we go our first symptom, which was also the day of his ER surgery. We read your book and are making his meals at home and found a vet familiar with Neo. He started his treatment 5 days after his surgery. HOWEVER, I have not been able to find one single success story, even in Dr. Fox’s case files, about Histiocytic Sarcoma. I keep reading pages and pages of stories about dogs beating cancer, but not one about a dog with maligant internal HS. Is it really that bad?? Do you know of any successes? Or can you recommend anything else that we should try? Thanks.

  • Lisa

    Hello Dr. Dressler,

    I have a 3 1/2 year old border collie/lab mix who was diagnosed with Nasal cancer from a biopsy done in February. Xrays were performed early on, January, to rule out a nasal obstruction and conluded that the entire nasal sinus was filled with tissue. The mass broke through her sinus passage and she has extreme swelling on one side of her nose, and bridge and raised so it somewhat blocks her one eye. We started on Neoplasine about 4 1/2 months ago, both oral and topical, and have seen some of the tumor fade away, one portion of the tumor fell off and left a hole. The open wound at this point is so large it takes up half of her face (bridge of nose, and cheek), and it appears to me that the neoplasine is eating away at healthy tissue. We use the wound balm as well, very liberally as it is unable to be bandaged due to her rubbing off the bandage. She wears a E collar when we put the neo on. My vet wants me to put neoplasine all over the open area, however when I do that the tissue that appears to border the tumor looks like it get eaten up, and my poor dog is in pain. It is very difficult to manage this area as some of the tissue looks as if there is bone protruding from it. My vet would like to me to be aggressive and attempt to pull off some of the dying tissue but it is really difficult to do so with her. They stated that they could surgically remove some of the tumor however are afraid that she will bleed out. Do you have any suggestions of how to manage this further? Thank you for your time.

    • http://DogCancerBlog.com DemianDressler

      Dear Lisa,
      this is tough. The Neoplasene is not destroying normal tissue- the cancer cells within the normal appearing tissue are dying. To be honest I think you might want to start focusing on life quality enhancement and keeping your dog as happy as possible. It sounds like this cancer is very invasive and will be difficult to deal with. If you would like other treatment options, consider radiation therapy, IV vitamin C with vitamin K3 (experimental but could discuss with your vet). I would also have you remember to use the supportive supplements too- apoptogens in particular. Have your vet supervise the use of the supplements. There is more info in the Guide that you might want to read about to help with life quality analysis and also treatment plan analysis.
      I hope this helps,

  • cheryl

    Hi Dr Dressler,

    I am writing to you from Malaysia.

    My beloved 15 year old dog could be down with Oral Melanoma Cancer pending final confirmation this week from the vet. It was heartbreaking when I heard about this 1 week back. There is no radiotherapy here in Malaysia and I understand that chemo does not work on this type of cancer. Besides, due to her age, I wouldn’t think this options are good for her.

    I was wondering if you do consultancy via e mail as to how best I should treat my dog from this cancer. I read about a vaccine called ONCEPT. Do you have experience with this vaccine and it’s effectiveness on treating dogs with this type of cancer? The reports so far seems promising.

    I have ordered you cancer survival book and it will be here in about a week. I am putting my dog on the diet recommended by you, the K9 Immunity Plus and have ordered herbal treatments to fight this type of cancer.

    Appreciate if you could do an e mail consultancy for me on my dogs cancer and the possible treatments available based on the restrictions here in Malaysia.

    Hope to hear from you soon.

    Thanks and Regards,
    Cheryl Wong

    • http://DogCancerBlog.com DemianDressler

      Dear Cheryl,
      the oncept vaccine is in use. best results with chemo as well. but available through US oncologists and I don’t know how you could get it to be honest.
      One treatment you might investigate with your vet is IV vitamin C with vitamin K3- seems to have some benefit with melanoma patients.
      I hope this helps
      D

  • Nicole

    Hi Dr Dressler!

    I have enjoyed reading your posts, as we are currently fighting the hard fight with TCC in our 8 year old Weimaraner. Daisey had a biopsy done on 9/17 and we are waiting impatiently for results, although our wonderful vet told us already that he feels strongly that TCC will be the diagnosis based on the appearance of the mass. Daisey has been having urinary straining and blood in her urine for ~1 month, and after two rounds of antibiotics we finally found a doctor who was able to determine that there is a tumor in her bladder, and it is large. Daisey started her piroxicam on 9/17 with the hope that we will be able to at least stop the growth. Our vet feels that surgery is very risky due to the size and location of the tumor, and he mentioned neoplasene bladder infusion as a possible treatment. Chest xrays showed no metastasis as of 9/12. My question is this; how effective is neoplasene in treatment of TCC? I am a realistic person, and I know that this cancer is terminal and she will die young from it. I would like to give her the chance to enjoy life for as long as possible, but I do not want her to suffer through treatment if there is a minimal chance that it will even help. Any advice is greatly appreciated! Thank you for all you do!

    • http://DogCancerBlog.com DemianDressler

      Dear Nicole
      so sorry you and your Daisy are faced with this diagnosis. There is some new info (human literature) that mitoxantrone with piroxicam is beneficial (not yet used in dogs but is something to consider with your oncologist). People have some successes with Neoplasene, but I would not rely on the bladder infusion by itself without also using the oral product. I would also consider DHA (discuss with your vet):
      http://www.ncbi.nlm.nih.gov/pubmed/21684140
      You would be well served to learn about the other steps (apoptogens, immune support, anti-metastatics, life quality enhancements, and so on) in the Guide, which will help sort out what is best for Daisy and for you too.
      Best
      D

  • Mary Benton

    My dog was diagnosed with stage II mastcell cancer. She is on prednisone, but it makes her pant. It looks like its hard to breath for her?I’am looking for some other alternatives, but at the same time I don’t want her to be in pain.Hope to hear from you. Thank you. Mary B.

    • Dr. Demian Dressler

      Dear Mary,
      there are other pharmaceticals (Kinavet, palladia and others) that could be tried under veterinary supervision. Also don’t forget apoptogens, diet changes, anti-metastic supplements, and the other tools in the Guide. Have you discussed your concerns with the veterinarian?
      Best
      Dr D

  • Carrie steckbauer

    Started my dog on neoplasene 3 days ago. So far so good. Her diet is now turkey, chicken, veges and brown rice. I also give her one fourth cup ice cream after meals, it is to help with absorption. In four days I am to double the dose. We marked her tumors, we hope to see them shrink soon.

    • Dr. Demian Dressler

      Dear Carrie,
      what kind of cancer does your dog have?
      Keep us posted!
      Best
      Dr D

  • BJ Stusiak

    Dear Dr. Dressler,

    On Oct 22 2011 one of my Basset Hounds was diagnosed with Lymphoma. We started Chemo on Oct 25. A friend of mine told me about a supplement called “PAwPaw Cell Regulator”. Do you have any insight on it? Our Oncologist said to go ahead and try it, but I am asking for any and all opinions…..

    Thank you, BJ Stusiak

    • Dr. Demian Dressler

      Dear BJ,
      from human use :
      “The active ingredient in paw paw extracts is a family of chemicals called acetogenins. These molecules inhibit the activity of the enzyme NADH oxidase present in the mitochondria and cellular membranes of cancer cells. The membrane NADH oxidase present in the membranes of cancer cells, tNOX, is inhibited by very low (nanoM) concentrations of acetogenins. The inhibition of this enzyme promotes both necrosis and apoptosis in cancer cells. Unfortunately, the inhibition of mitochondrial NADH oxidase rapidly depletes ATP in BOTH cancer and normal cells. This makes paw paw extracts TOXIC to normal cells if taken in excessive concentrations.

      I have a fair amount of experience working with paw paw, but I dropped it from the cytotoxic protocols due to its poor bioavailability and potential toxicity.

      Although there are many testimonials on the Net claiming that paw paw extracts “cured” their cancers, I am very skeptical. On the other hand, there may be some truth to these statements. Acetogenins kill cancer cells by reducing ATP and glutathione levels and inducing oxidative stress. If a person is taking anti-oxidants along with the paw paw, the clinical efficacy of the paw paw will be neutralized..”

      The author of this blog (who passed away last year) generally has intelligent things to say and had a rather large following of human cancer patients who tested on themselves a large variety of “alternative” therapies.

      If you are interested in dog cancer supplementation, there is a large body of research in the Guide that would be of benefit for you.
      Best,
      Dr D

    • Dr. Demian Dressler

      Dear BJ,
      see my answer to the other post,
      thanks
      D

  • Tiffany

    My Mom’s great dane, China, was diagnosed with oral fibrosarcoma in 2010. The tumor was huge. She is from a small town, and when China was about a year old, my Mom took her to the vet with the first signs of the tumor. The vet visually examined it and said it was probably OK, to just keep watching it. I don’t know first hand what was discussed between the vet and my Mom, but two years later the tumor had gotten larger and had ulcerated. She took her back to the vet and now we had a very advanced fibrosarcoma with roots up into her sinus and ocular cavities. The vet sent us to a board certified veterinary oncologist and surgeon. They pretty much said we had between 6 mos and 12 mos if they were able to get everything surgically. Nothing showed up in the lungs. Surgery was very difficult and we almost lost her in recovery. They said they got everything and anything left would be microscopic.

    3 mos later, at China’s followup CT scan, it showed the cancer was back and “eating the bone.” My Mom was in hysterics. The Oncologist said we could try radiation, which meant we would have to send her away for 1-2 months where they would have to put her to sleep every day for treatment. That may only give us an extra 2-3 months with her. We asked about Chemo and they said there was nothing really. We found out about Neoplasene and the Onc. said NO WAY, that stuff was “dangerous” and she highly recommended we didn’t do that. Then she said, well, if you want to try something, we could use this radioactive seed implant – the same stuff they use for prostate cancer. I checked that out online and there was no info to be found using it for oral fibrosarcomas! The only thing I found was suspicion that it caused fibrosarcoma in one situation. We decided we would ask our local small town vet to work with Dr. Fox. They were happy to try anything because they are so attached to our beautiful China and want to do anything to help.

    My mom followed the instructions, but a couple of months later suspected the calculation of the dosage was too low for her weight and started adding a little more. The local vet said it was correct and Dr. Fox was pretty short with her and said to follow her vet’s instructions. She did, but 3 months into the treatment China’s mouth started bleeding and she was vomiting with some blood in it (This is most likely because my Mom was giving her too much – against the instructions). She took her back to the oncologist with the worst fears.

    They did a third CT scan, and when they came in with the results, my Mom was crying so hard. They said, “Why are you crying? There is no cancer!” We couldn’t believe it. They couldn’t believe it. They sent all 3 CT scans to an expert and he confirmed that the first CT showed lots of cancerous “roots” (pre-surgery), the second showed where it was coming back (3 mos post-surgery), and the third showed no cancer at all (3 mos post-neoplasene). It was official, and whether they want to think it miraculously disappeared because of the THREAT of radiation and radioactive seeds, well wishing, or admit it was due to the neoplasene treatment is up to them. I hope they recommend it to some other patients, but I’m pretty much 100% positive they will not.

    All of this started in June of 2010. It has been over a year since the Neoplasene killed that cancer. I believe the surgery was necessary. There was so much cancer in her upper jaw that it had to be surgically removed. China is still doing well. I hope you all will consider it. Dr. Fox can be a little (or a lot) rough around the edges, but for goodness sake, deal with it and get the stuff. You have him work with your vet anyway. He talks with countless hysterical dog mommies and daddies every day. Surely that would make anyone go a little nuts after a while. Heck, if I had cancer, I’d get it for myself!

    • Dr. Demian Dressler

      :)

  • Nancy

    My 9 year old black and tan coonhound has a huge tumor on her left shoulder next to her neck. It has been removed twice and returned twice. It was diagnosed as a hemangiopericytoma. We checked into radiation treatment but did not follow thru as the closest radiation for dogs is about 4 hours away and Maggie gets car sick. This week, I noticed the tumor had erroded and a small hole appeared, draining fluid and bloody discharge out. Our vet suggested we talk with a second vet in our area who uses neoplasene as a treatment. My question is, is a treatment with neoplasene going to help Maggie or make her days filled with pain; she hates the bandage and has had no success wearing an e-collar as she rips them off. We are meeting with the vet on Monday to see what she says, but I was wondering what you thought. I do not think the cancer has metasisized due to the clean chest xray taken recently.
    thanks

    • Dr. Demian Dressler

      Dear Nancy
      under the circumstances I would give Neoplasene (as well as Apocaps, dog cancer diet, immune support, anti metastatics, and the other important steps discussed in the Guide) a try under veterinary supervision. The question becomes if not these approaches, what can be done? Without surgery, radiation or chemo, we have to consider other options. Also consider Matrix 3 cisplatin impregnated beads. Please use veterinary supervision for all your treatment steps-
      Best
      Dr D

  • Rebecca W

    Dr. Dressler,

    My 6 year old cocker spaniel was diagnosed with Subcutaneous Hemangiosarcoma of the left leg. Prior to it being diagnosed as hemangiosarcoma, Lily had the tumor for at least 6 months but the regular vet said it was just a fatty tissue. However, once it became larger, we decided to get it biopsied. The tumor was removed without clear margins and we began intraveneous chemo and radiation treatment. During this process, the tumor began to grow in the face of chemo. The oncologist then did a “flap” surgery to remove the tumor and took skin from her stomach to cover the wound. The surgeon felt the margins were clean and that the tumor was completely excised. At that point, we started doing oral chemo 3x a week. About a month ago, I saw that the tumor was coming back. The vet did a biopsy and found it to be the hemangiosarcoma coming back. We stopped the chemo at that point and I have put Lily on chinese herbal supplements as well as a raw food diet. I am wondering what would be a viable option for treatment ..ie neoplasene topically applied. There seems to be two tumors on her left leg (the size of 3 grapes combined). I am not sure if we should let her live her life out or persue other treatment. We have spent so much money and I feel our options/ time is running out. Any ideas/suggestions would be appreciated. Also, Lily was diagnosed in late march 2011 with hemangiosarcoma. She has great energy and appetite..I am not ready to let her go..but I do realize that this is a terminal illness.

    • Dr. Demian Dressler

      Dear Rebecca
      you have many things going on in this question. First is the question about what else is there to do. For this I would have you read the Guide, which is why it was written:
      Diet
      Apoptogen combination
      Immune support (beta glucans, etc)
      Consideration of oral neoplasene (under these circumstances)
      Antimetastics (modified citrus pectin, etc)
      Brain chemistry modification
      Deliberate life quality increases daily
      etc, etc
      Then you have a treatment plan analysis, also covered in depth in the Guide. Here is a blog post for you:
      http://www.dogcancerblog.com/what-is-treatment-plan-analysis/
      and finally, you are not ready to let her go, which is understandable! Another related post for you
      http://www.dogcancerblog.com/i-can-see-the-end-but-i-am-not-ready/
      I hope these help
      Best
      D

  • Nancy F. Topping

    Thanks for your advice; we did meet with a holistic vet on Monday and they also recommended the Neoplasene treatment and after pre op exams, they think she is a good candidate for surgery, so they are debulking the tumor on Thursday followed by Neoplasene treatment and the vets office will be following up with the bandaging and other things. They have also put her on some “tea” pills and an antibiotic, and a diet that does not include dry dog food, so we shall see how this works, I hope things are ok and she does ok with the surgery and treatment; we decided having her survive was our gift this year, thanks again

    • Dr. Demian Dressler

      Good luck Nancy
      Best
      D

  • Audrey

    My 121/2 yr old Labrodoodle, Togo Bear, has fatty tumors. He developed another similar one on his left upper neck. It has grown slowly over the last year and is under the skin. He shows no signs of being sick. I showed it to 2 vets. The last one drew a sample and said it was a cancer. I am not sure what kind. I am now researching as Togo is in great health, eats well ( I make his food), and loves his daily hour plus long runs at the big dog parks. He however does cough like clearing his throat when he lies on his left side. So I don’t have much info. I am making an appointment with a holistic vet in town. This appears to be slow growing. What sort of tumors is this not recommended for?

    • Dr. Demian Dressler

      Dear Audrey,
      I am sorry about Togo Bear. I think it is important to find out what kind of tumor you are dealing with here, as it can help us with treatment recommendations, as you will read about in the Guide.
      I think this might be an important post for you to read about the benefits of intervening before dogs start acting sick from cancer:
      http://www.dogcancerblog.com/signs-of-dog-cancer-and-decompensation/
      Please let us know the cancer type and we will usually respond within 1-2 weeks.
      Best
      Dr D

  • Byron

    My dog is 12 years old American Eskimo, he was diagnosed with squamous cell carcinoma prostate cancer Feb 2011, at the university of MN animal hospital they gave him until summer of that year, we have been giving him neoplasene, and thuja, also cass options, I would like to know how long he can be on the neoplasene it has been 1 year, we have stopped for awhile to give him a break, we also have a feeling he might have lymphoma instead of prostate cancer his calcium was down and now it has started to climb a little we don’t know if the holistic vet we are seeing will put him back on it, he is doing really good and walks 1-2 miles a day and also eats a lot , he never has a hard time going poop or peeing, please any ideas?

    • Dr. Demian Dressler

      Dear Byron
      if it has worked, keep it up. I would also be using the other tools in the Guide including other apoptogens, immune support, diet, antimetastatics, and brain chemistry modification.
      D

  • Byron

    My American Eskimo is eating and drinking and walking 3-4 miles a day and is very alert maybe we fed him something with to much calcium in it. Cantoulope, and squash wich are high in calcium, he is on a no grain dog food wich helped turn him around, changing his constitution Chinese would say. No red meat just fish and chicken. Any ideas?

  • http://www.indyandcaninecancer.blogspot.com Jennifer (Indy’s Mom)

    Just wanted to say that we’re using Neoplasene and it’s been WONDERFUL! It’s saving our dog. We understand that he will be on it for the rest of his life. It’s not a cure, it’s a treatment. He was diagnosed with Histiocytic Sarcoma, a very aggressive and always fatal cancer. He was treated at UPENN and we were told to expect no more than 4 months. It’s now been 7 months and Indy is happy and cancer free as of this week! He had an x-ray and ultrasound done and they can’t find the cancer! No side-effects and a playful puppy. It’s been amazing! Best of luck to everyone!

  • KTS

    Hello. My dog Louis has hermangiopericytoma cancer on his chest. It is as big as a cantaloupe right now. He is 11 years old and very happy and active despite this. He still loves to play, run, jump in the car and go for rides, chase cats and eat like a pig. I was wondering if neoplasene would be a good treatment for his type of cancer. Thank you for your help.

  • Casandra

    I have a two year old Husky who is like a child to my boyfriend and I… We treat her like a princess. We found out recently that she has a tumor on her back right leg because of placement they are saying they will have to amputate her leg because they cannot remove the tumor and have enough good cells to place over the contaminated area. Can you explain in lame terms how we would go about asking our vet to try this for us. Also what is the procedure? Is the neoplasene injected into the tumor and as it opens and falls off the skin underneath is producing new cells? I would love some guidence we have never been thru this before and are extremely worried about our loved one.

  • robert

    dog has sarcoma

  • Korine

    Dear Dr. Dressler,

    My dog was recently diagnosed with a nasal tumor, and on Tuesday he had SRS performed at UF. Your book has been immensely helpful as I deal with this diagnosis and weight the options, so thank you. His main complication is that the tumor has eaten through the bone at the top of his head and produced a bump. The radiation oncologist wasn’t able to concentrate as much radiation on the bump, and while we don’t know what’s going to happen yet (follow-up CT scan in 3 months), I’m prepared for an eventual recurrence at that bump.

    A holistic vet here recommended Neoplasene as an option for the tumor, but she doesn’t have much experience with nasal cancer. Do you see him as a candidate for Neoplasene? Or what questions should I ask? My concern is that if the Neoplasene works, he’ll end up with a hole on the top of his head where the bump currently is since the bump is tumor and not bone.

    I would appreciate your thoughts if you have time.

    • Dr. Demian Dressler

      Dear Korine
      this sounds very tough. You may indeed get a cavity. You ought to be able to look at the CT to asses the bone involvement and determine a rough amount of available normal bone. I would team up with the imaging person and discuss that. Might do oral neoplasene only (no topical) with half dose apocaps, to curb growth instead of cause cancer cell death, in order to preserve the structure. I hope this helps. Talk to your vet and onc…best
      Dr D

  • PJ

    Casandra,
    My dog is a Bloodhound/Chow Mix (90lbs), he will be 11years old in June. Last February (2011) we found tumor on his back right leg. On March 1, 2011 we started treating him with Neoplasene given orally and within in months the vet said that the cancer was gone. He is still taking the Neoplasene and he has a callous where the tumor was, no hair grows there, but his doing fine.

  • Korine

    Dr Dressler,

    Thanks so much for taking the time to reply. I’m glad to have some more info to take to the team of vets working to help Jasper!

    Best wishes,
    Korine

  • Margaret Arline

    Dear Dr. Dressler,

    I would like to know if Apocaps can be taken simultaneously with Neoplasene Oral treatment and/or during Neoplasene bladder infusions. My dog is recently diagnosed with TCC and I’m evaluating my options. I’m reading your book and already am incorporating the diet – though I’m waiting for a few supplements in the mail. Any insight will be much appreciated. Thanks in advance.

    -Margaret

    • Dr. Demian Dressler

      Dear Margaret,
      A good question. This combination has not been studied formally, and at the time I wrote the Guide I was not comfortable with the combo. However, since then I’ve used the combination in about 15 dogs in very severe situations and have not seen adverse effects related to the combination. Having said that, please be sure to have veterinary supervision.
      All my best
      Dr D

  • Catalin Pirvu

    Hello Dr. D.
    My name is Catalin, I’m from Romania, and I own a labdrador metisse with the age of 10 years.
    Soonly has been diagnosticated with bone cancer (osteosarcoma) and I’m desperate, that ii don’t know what to do him…
    We’ve been walkin and waling around to all doctors and they toled us that there is nothing that we can do for him…:(
    In my reasearches, I found your blog and now I hope that we can do something for him.
    Please! I’m beaging you, help me to help him! Help us!
    You can write me back and my mail adress catalinpirvu87@yahoo.com.
    Please make it as quick as possible, and if u can, leave me a phone number where I can get in touch with you!

    Thank you!

    • Dr. Demian Dressler

      Dear Catalin,
      this blog is for the benefit of the dog community. Please post your question so all can benefit,
      with thanks
      Dr Dressler

  • susie

    I have a collie dog who has a tumor on her mouthiit is out side the mouth it was the size of a golf ball, it smelled and was bleeding , we took her to the vet he started her on treatments with the neoplasense, and have a salve put on it after treatment, it is buck mountain herbal gold , get 2 treatments aweek, it works she has been doing these for maybe 8 mo or more, and it is down to the size of her mouth , it is amazing

  • JOAN

    I have a big 147 lb working AMBD recently diagnosed with 2 mast cell tumors, just under his skin with hair and no redness. One tumor is the size of a pea, the other a peach pit. He is 6.5 yrs old. I could find only one vet willing to remove the two tumors (due to his large size they said) and His total estimated costs were well over $12,000 dollars. He also said even though one tumor was small, he probably would have to take the dog’s leg and that the tumors would probably reappear. I just ordered your book and apocaps. I have my dog on the diet you suggested online and he is tolerating it well, but coughs once or twice after eating. I question if it is due to him eating the food so fast that he coughs as my husband thinks or probable pathology related to the tumors. My dog loves the cancer diet and never ate dry food anywhere near so fast. He is on 400 mg tagamet and 50 mg Benadryl BID(which puts him to sleep fast) so far for one week. I would like to add Vit C and possibly prednisone to his routine if worthwhile to try. However, I am wondering if you could give me appropriate advice as to dosages. Five weeks ago he weighed 150 lbs, but since he is no longer eating dry dog food he has slipped to 147 lbs. How long do I keep him on this protocol? How important is the surgical removal of the tumors? They were needle aspirated but I can’t find a vet to take the next step and remove them and stage them, except for the one previously mentioned. I am disabled and raising my granddaughter and cannot afford the surgery. How does leaving the tumors, but doing the diet and suggested benadryl/tagamet treatment affect survival rates? Also, can I add a cooked egg to my dog’s daily diet? He so loves eggs. I was told 8-9 yrs would be good lifepan for a dog of his size without cancer. Do you have any other suggestions that will help me get him to 8 without undue suffering? I am a registered nurse, specialty certified in oncology and orthopedics. Please be as technically specific as necessary. I will precisely follow your suggestions, finances permitting. I asked the surgical vet about your suggested protocols and he was skeptical and wouldn’t read the literature I tried to provide him, so asking him for dosage amounts is not an option. So if prednisone is a good idea, I will need suggestions as to how to get the vet to sell me some, since he doesn’t think much of the Benadryl/Tagamet treatments and wouldn’t read the literature and appeared to have no interest in doing so. He said he gave prilocec for stomach upset in later stages but that was it. Thank you so much

  • Jane Bentley

    Dear Dr. Dressler,

    Our 10 yo – 90 lb Doberman, Shelby, has osteosarcoma in her distal radius. Her lytic lesion was the size of a golf ball about 6 weeks ago and is now about the size of an lime. We opted against amputation, chemo or radiation and after 2 rounds of leg and lung x-rays, there is no evidence of any metastasis. Shelby limps badly, but is still as vibrant, happy and hungry as ever. We fight to keep her from running around and playing with her sister, knowing that if/when the leg breaks we cannot let her suffer.

    Between her oncologist and our prior regimen, Shelby is on intensive herbal blood and immune support with massive artemisinin and specific bone support enhancements, and Tramadol with Gabapentin as needed to keep her comfortable. We’re also praying for a miracle as she is my teenage son’s angel companion.

    I have the “original Amazon cansema Black Salve” shipped from Equador and am afraid to use it topically knowing the immense bone damage already done. I was encouraged to give her “orally a 1/2 small pea size amount twice daily” to kill her cancer as the neoplasense would.

    My concerns are, given “internally” would the outward tissue damage be as extreme or will she still have a massive open crater where the tumor was, and could there be enough bone remaining to allow regrowth and support her weight.

    We do not want to chance that the pain and distress from such a potentially massive open wound would shorten her life more than the cancer will. But if given orally will lessen the outward tissue damage then it may be the miracle we hope for?

    Please give me your brutally honest medical opinion as we know we are running out of time to help her.

    God Bless You for your generous help to loving owners like us!!!

    JANE

  • Linda

    Here I am with my little 7 pound toy poodle, thinking we are seeing our last night together, and Im still researching cures. My homeopathic vet persuaded me to not do surgery, and her growth has grown from a pea size, to a baseball, over 5 months, on her lower tummy, with a 1 inch deep opening. She just stopped eating today. And is weak.
    I am wondering if I should try the Neoplasene at this stage.
    She is on Morphine.If the Neoplasene could be of help, then I will try it.
    My dog seems to be at peace, is very weak, and we are happy to say goodbye, knowing that she will be in heaven, but if we can help keep her with us , as I have been reading about others, than we could try the Neoplasene.
    Thank you for any advice.
    Linda

  • Melissa

    Dr D.,
    Our 7 year old coonhound mix, Otis, was diagnosed with osteosarcoma on August 31. Our primary vet told us it had already metastasized to his lungs, and there wasn’t much we could do. I quickly started researching and came across your book (It really has been a godsend!), which I read as quickly as possible and started implementing the home cooked diet along with Apocaps, k9 Immunity, acupuncture, and some other herbal supplements. Thankfully, Otis doesn’t appear to be in pain.
    We decided to see an oncologist, who disagreed with the original diagnosis. It hasn’t metastasized to his lungs; what was appearing on the chest X-rays were mineral deposits. In light of the new information, she recommended amputation and chemo. We asked about Neoplasene, and she said to avoid it like the plague.
    On the same day of this recommendation, we had a phone consultation with a holist vet. The main focus of her practice is dog cancer, and she treats it with Neosplasene, diet and supplements through phone consultations in conjunction with working with a local vet. She is saying Otis can make a full recovery with no surgery.
    With the polar opposite opinions on treatment, and the fact that many vets are at opposing opinions on Neoplasene, we have no idea which treatment path to choose. Is it possible to try Neoplasene for a while to see what happens, and if it doesn’t work, or Otis can’t stomach it, THEN go the amputation route? Or is it too risky to wait to try an alternative therapy?

  • Stacey E

    My dog recently had neoplasene treatment (by injection) to a tumor that has grown back three times. She has been in excrutiating pain for three days now. I resent being talked into a treatment that is doing this to her. She could be a fairly happy dog right now with an untreated tumor, yet she lays on the floor howling and barking from the pain she’s in. Pain pills are doing very little except making her glassy eyed. Worse still is that we paid over $500 for the treatment, and she may have to be put to sleep because it may have caused her to have a stroke, because she can no longer hold herself up.

  • Christine Schulte

    I was given Neoplasene for my dog from the vet who is also a chiropractor for dogs and horses. I BEG EVERYONE NOT TO USE THIS TREATMENT if you love your animals the way we do. I gave my dog one dose and she went absolutely wild. It was like she was on fire. She paced and panted for hours. I called the vet after 4 hours and she said the drug must be working! THIS IS THE MOST INHUMANE TREATMENT I have ever experienced for an animal. The vet then prescribed valium to claim her but it took a while to kick in. I immediately called another vet for a second option whom then set me to an oncologist. Oncologist have humane treatment methods. The cancer had already matasitsized an the Neoplasene would not have been the mircle cure anyway. THIS IS A HORRIBLE DRUG and should be removed from the market.

  • Terry

    I used Neoplasene for my 6 year old Lab who had a mast cell tumor on her belly. It was amazing. We injected the medicine around the tumor and within the week, it started to eat away the cancer cells and leave the healthy cells alone. I watched it with my own eyes! My dod was only uncomfortable for about an hour but after that she never felt any pain. It did leave a 2 inch hole in her belly but all I had to do was keep it clean and it closed up on its own within a month. Now, we have a 9 year old German Shepherd with bone cancer. We are trying it orally. It’s too soon to tell if it is working but so far he is in great spirits, eating healthy, no problems with breathing and still wants to play. Yes, he is limping and not using his leg, but that is because the tumor in in his front shoulder. He is currently on one pain pill a day just in case.

  • Garry Sheen

    If Kathy is still using this blog, I would be very keen to know how successful the neoplasene bladder infusion was with her dog. Would really appreciate any feedback, as I considering this for our dog, Logan.

    Kind regards

    Garry

    “dog was diagnosed with a TCC bladder tumor. My vet has been treating him with 5mg piroxicam and bladder infusion therapy of neoplasene. ………….

    Thank you,

    Kathy”

  • Kimberly

    My 12yr old husky has nasal cancer, he weights around 47 lbs. currently he is on antirobe and previous and takes thyroid pills. Currently he is running jumping eating and very happy. We can’t afford radiation or chemo so our vet recommended neoplasene to be taken orally. I don’t know what to do I am reading to many conflicting statements on this drug. Please I don’t want to cause him any pain when he isn’t in any, yet I want to shrink the cancer if I can. I have pain meds for when the time comes should he be in pain,but not sure if I should keep him on his current meds or try Neoplasene. This dog is my child I don’t want to do anything to harm him,and I am afraid to do nothing. Help thanks

    • Dr. Demian Dressler

      Dear Kimberly,
      always use an anti emetic med for vomiting with that treatment, i use mirtazapine. Discuss with your vet please. Secondly, I would start here for more optionsL
      http://www.dogcancerblog.com/an-overview-of-what-else-can-i-do/
      Other options to discuss are apocaps (i usually use half dose with neoplasene), high dose IV vitamin C, diet, beta glucans, and so on.
      I hope this helps
      Dr D

  • Miriam

    My Siberian Husky was recently diagnosed with nasal carcinoma. The tumor fills her entire right nasal cavity (with turbinate destruction), and in some areas, the left as well. Radiation is not an option where I live, so I have been searching for other options. I went to a holistic vet, who recommended to start her on different Chinese medicines (Max’s formula, Stasis breaker, and mushrooms). I am a little bit skeptical because I don’t understand how the different Chinese medicines work on the body, and I can’t really find much information on them. I have also read about Neoplasene. Do you have any thoughts on “alternative” therapies for a dog with nose cancer? Thanks so much!

  • http://dogcancerblog.com Berdine

    My 14 year old Pyranees has a tumor on the side of his neck. My vet suspects cancer but, waiting on test results. She has suggested neoplase instead of surgery. At his age would he do better with neoplase than surgery? Is neoplase painful when eating through the tumor. I know my dog is older but, can’t give up on him.

  • Erin

    My Golden Retriever who is 9yrs old, was just diagnosed with hemangiosarcoma. We were able to remove 95%of the tumor on his heart valve yesterday. Hoping the recovery of the surgery continues to go well, and in the meantime we’ve been starting to look into different treatments to stop the cancer from spreading/growing as quickly. Chemo has been the main option. Just wondering if anyone has used neoplasene for hemangiosarcoma tumor on the heart? I’ve read a bit into Addies story which is quite remarcable. but from I can tell she just had the tumor on the spleen. Not sure if it could have the same positive effects on my boy. Anybody who can help or throw any advice my way, please do! I’m willing to try anything to keep my boy up and going as long as his quality of life doesn’t go down.

    • Dr. Demian Dressler

      Dear Erin
      I would be leaning towards Apocaps, low dose oral neoplasene combined with mirtazapine, metronomic palladia possibly, and either ImYunity or K-9 immunity with transfer factor..and of course diet…all under veterinary supervision….
      I would read the Guide as each is discussed.
      I hope this helps
      DR D

  • rebecca

    Dear Dr. Dressler
    neoplasene and apocaps combo: I have read a previous post where it was stated that both were used simultaneously in dogs with serious conditions. Today we started neoplasene and we’ve already been on apocaps for 4 days. Our male standard neutered poodle, age 9, is s/p splenetomy, DX lymphoma with 2 rounds of chemo which our vet assured us would not be beneficial after a subsequent DX of poorly differentiated cells in the synovial fluid of his RFE, sudden onset of lameness, indicating osteo. I started him on your diet suggestions and purchased the cancer information package. Today he received a dilaudid IM and fentanyl patch. I’m just not sure what to do. I have seriously considered euthanasia, but he is fighting so hard and his appetite remains phenomenol. He has 5 pack siblings. Radiation due to begin on Thursday and on and on and on. What should I do, really, I do not want regrets haunting me. Thank you for all that you do for the critters!

    • Dr. Demian Dressler

      Dear Rebecca,
      so sorry to hear this tough news. Be sure you are using mirtazapine or some other potent anti emetic or you will risk some pretty serious tummy issues with oral neoplasene. Having said that I have been using the combo of oral neoplasene with apocaps pretty frequently for about a year now and things seem OK…but as usual have your vet supervise all you are doing to be safe. Let us know how it is going and don’t forget immune support and I might throw in some extra silymarin with the radiation, personally.
      Dr D

  • Kathy Cutler

    Hi, I would like your input on how I am treating my dog Sammy. He had his spleen out about 3 weeks ago., a small tumor was bleeding into his abdomen. The surgeon saw a tiny nodule on his liver so he biopsies that. Both the spleen tumor and liver came back positive for hermangiosarcoma. The Dr. Told me that Sam has about 3-6 months of a quality life until the liver starts to bleed as the spleen did.

    I am now taking a holistic approach. Sam is no longer eating his Pro Plan dry, he is getting all meat and veggies. (I have noticed that there is a lot less stool to pick up.) the Dr. I spoke with advised of the diet., we put him on Artemisinin, wearepulsing that.,so many Dayton, so many off etc. The next step is to start the Neoplasene. I just received this yesterday from the receptionist., I did not speak to the Dr. About any side effects etc. But she did hand me a paper with the website LeonbergerHealth.com and told me to research and read it. What I have is a liquid. Can I put this liquid on a treat that he loves to get him to eat it? (Chewy and Stella’s freeze dried treats.) VERY HEALTHY.

    Also, I found a great product that will pull all toxins from your body and have started Sam on that. It’s called Zeolite, in the powder form. He can take this with other things and has no side effects. I asked the receptionist to tell the Dr. About this, but I haven’t heard a word from her. I expressed my feelings in an email that this is all new to me and I do not want anything to happen to our son. He is 7, a lab mix.

    I was told no carbs etc., however was just told yesterday to give him mainly sweet potatoes with other veggies and meat once we start the Neoplasene. Sam is great at spitting out the veggies. I cooked up broccoli, kale,cauliflower for him. He is starting to catch on!

    I thank you for your input. I want to know if what Iam doing is good for Sam, I feel like I alone with this treatment sine the Dr. Seems a little hard to get a hold of anther emails are quite short.

    Sam is also on an Immunity Booster.

    Thank you!!!!!!!

    Any pointers you can give me would be wonderful.

  • Stephanie S.

    Hi Dr. Dressler,
    On April 12, 2013 my 11 year old (approximate age) mixed breed (possibly border collie/labrador) dog, Highway presented with a swollen area on the left side of his nose (2 inches long, 1 3/4 inches wide, and approx 1/4 inches high in the center). X-rays showed a mass above the gumline, and a fine needle aspirate came back inconclusive because of blood contamination. Assuming that the mass is cancer (I decided not to get a tissue biopsy), I’ve started him on your diet (not fully implemented yet), and other recommended supplements according to your guide. He began Apocaps and K-9 immunity on 5/4/13. I also have him on Primalix Immune support and Primalix Anti- Cancer drops twice daily with meals. I am wondering how soon might I be able to tell if the diet and Apocaps regime are working, and if the regime is not working, would Highway be a good candidate for low dose oral Neoplasene? Aside from the mass, Highway seems to be doing quite well with good appetite, good energy level, high spirits, and is accepting the new diet and supplements regime very well. Photos of Highway’s mass can be viewed at the following website:
    http://thefoff.com/pix/thumbnails.php?album=42
    Dr. Dressler, I would greatly appreciate any advise and recommendations that you can offer me for Highway. Thank you for all your efforts to help our beloved dogs.
    Stephanie

    • Dr. Demian Dressler

      Hi Stephanie
      I am sorry to hear about your dog’s nasal tumor. :(
      I would discuss not only what you have already begun, but also possibly palladia or piroxicam. If using piroxicam, drop the apocaps to 1/4 -1/2 the labeled dose, and discuss all these steps with your vet. I would yes, also consider low dose oral neoplasene along with an anti emetic like mirtazapine.
      I would also consider perhaps doxycycline under veterinary supervision…you will need to hit this hard as these tend to be aggressive.
      Hope this helps
      D

  • Stacie Bowes

    Hello:

    My golden, just got diagnosed with a nasal tumor, the pathology reports are pending on what type. I prayed it wasn’t this, but my intuitions were right, unfortunately. I haven’t even crossed the bridge of other treatments, but I am really interested in neo and if it works for nasal tumors. I pray it is not cancer, but I can’t be blind to this anymore. I don’t want to put him through radiation and frankly, I just don’t have the cash. He is my world, I work from home and the thought of him not being here is killing me. I am mad, hurt, devastated, lost and just not sure what to do now. He is only 6.5 years, I thought we had at least 5 more years with him. Is my vet going to knock this down when I ask about it? I am in PA and not sure of any holistic doctors around here. I just need someone who knows what I am going though to help me ease the pain!

    Stacie

  • Cheryl

    Hello,

    My 11-year-young Shetland Sheepdog, extremely fit and active, has been diagnosed with Lymphoma. Her lymph nodes on either side of her throat are about the size of two marbles and the nodes above her shoulders are about like cherry tomatoes. Nothing felt in the abdomen, groin or behind the knees. Pathology shows about 50% of her cells from the biopsy are the enlarged Lymphoma cells. Do you feel that Neoplasene would be of benefit to her? I’m simply devastated looking at my otherwise perfectly healthy and happy dog and thinking that the end could be near for her. Any help or advice is greatly appreciated. Thank you.

  • Nicole

    Cheryl,

    I’m treating my dog with lymphoma and exact same as you described. I’m using Neoplasene as well as mirtazapine, and prednisone. She’s made it a month so far and loves her new cancer diet. She looks pretty good in the eyes, but her face has become deflated from the pred. which saddens me to see, but her swelling went down almost instantly when put on it. Pred is a mask though and other things are still going on and her body is slowing. I was told I may only have a few months with her so we are trying to make the most of it. She still has her appetite so I know she is ok. Once that goes I know she is failing. She struggles some days with heavy breathing and it’s usually after a dose of neoplasene. She gets warm to the touch and then after several hours calms down. I give it orally. I hid it in her food as she hates the taste! She is on Apocaps, K9 Immunity, and Wobenzym. It’s very hard to know on her hard days weather its her cancer or the treatment bothering her. We try to keep things calm and I just know she may never be the same dog again. We limit rides in the car, which we did several times daily. Now we go days without going and it’s sad. I try to look at it as a time out vs a forever. But some days we just ride around and come home. She doesn’t walk near as far without needing water. Before she could go several hours or 1/2 day without water. She is noticeably different. I am fasting myself in order to clear my own body so that she feels no extra anxiety from me. I keep soft music on (monk chanting in fact) and we have a pretty sen life right now… Sending love!

  • Savannah

    I have a 7-year old Great Dane who is everything to me and I just found out that he has a bone tumor(osteosarcoma) in his front left leg that is enveloping the ulna. Amputation is out of the question because of his large size and my vet has essentially just given me enough pain meds to give him until the end. But I’m searching the internet trying to find out if there could possibly be any other options out there for us. Even just something extra and topical I could use for the pain. Or something that could slow down the growth of the tumor. Essentially any other advice or help of any kind would be more than appreciated. Thank you.

  • Susan Kazara Harper

    Jesse, these are the hardest times to go through. The bottom line is that no one can make this decision for you. You have fought hard and it’s obvious that you love your boy very much. You also know him better than anyone. I encourage you to sit down with him and just be still. Take a few deep breaths, and calm your mind, listen to your heart. Talk to him, tell him you are doing everything you can for him because you love him and want him to get better if he can. But also Jesse, every living being has a time to move on. Sometimes our animal companions love us so much that they fight really hard because they know we are too afraid of losing them. And that can become a burden to them. If you can take the pressure of your fear off your boy and ask him to let you know what he wants, you will very likely feel the answer in your heart. Sometimes just relaxing our own expectations and needs allows our animals to relax and feel a bit better, and sometimes it allows them to feel it’s OK to move on. When you talk to him, make sure you take the opportunity to laugh as you tell him how much joy all the years have been together. If you can step back from your grief, you will know what decision to make and when, and it will be from your boundless love. Give your boy a hug from me, and one for yourself.

  • Weslee

    I have a cat with what my vet and I are assuming is an injection related sarcoma between his shoulder blades. After watching a tiny lump for a year, it suddenly grew into the size of about a Ping-Pong ball. Would he be a candidate for topical Neoplasene? We do not want to do surgery or chemo/radiation.

  • Dr. Demian Dressler

    Dear Beth,
    chewing of the skin is not a sign of pain necessarily, and there may be little connection to the tumor. There are other more common causes of skin itch like fleas, allergies, skin infection, yeast, etc. I would check with the veterinarian to rule these out first and asses whether this has a connection with the tumor or not.
    Have you started your dog on the dog cancer diet, supplements, and so on in the Full Spectrum plan?
    D

  • Sandy

    So sorry to hear about this story. Are you saying that you gave your dog the treatment? I thought that Neoplasene was only to he administered by a vet? Also, I read that it should be given with pain meds and a special balm that goes with it, as well as other drugs (narcotics and non narcotics) that vets have at their disposal. Valium is only a tranquilizer and not really a pain medication, so it would, I think, be totally unable to control the situation. This is not your fault, but rather the vet for putting you in charge of something that he/she should have been doing and managing.